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GI > Ulcerative Colitis > Flashcards

Ulcerative Colitis Flashcards

1
Q

Aetiology of UC

A

Th2 dominant

IL-5

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2
Q

Macroscopic Pathology of UC

A

Affects colon only
Continuous involvement
Red mucosa - bleed easily
Ulcers and pseudopolyps

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3
Q

Histology in UC

A

Mucosal inflammation
No granulomas
Goblet cell depletion and crypt abscesses

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4
Q

Clinical features

A

Diarrhoea - blood and mucus

Can be persistant, relapses and remissions or severe fulminant colitis

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5
Q

Complications of UC

A 
Toxic dilatation of colon and perforation
Stricture formation
Abscess formation
Fistulae and fissures
Colon cancer
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6
Q

Indications for surgery - UC

A

Failure of medical therapy
Complications
Growth failure in children

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7
Q

Surgical Procedure performed in UC

A

Colectomy with ileoanal anastomosis

Panprotocolectomy with ileostomy

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GI (5 decks)

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