Udder Anatomy Flashcards
Name the anatomy of the udder?
Cisterns, Ducts, Lobe, Lobule, Alveoli
Name the Milk Protein Secretion Pathway
nucleus > rough ER > smooth ER > transport vehicle> cis side golgi > sorting > secretory granule > transport vehicle > cytosol > PM
Name the milk fat secretion process?
adding 2 layers of phospholipids once CLD (cytoplasmic lipid droplet) meets membrane
Milk Synthesis Pathway
milk synthesis by epithelial secretory cells
blood supply via arterioles, capillaries, venues
capillary filtration via lymphatics
milk letdown by myoepithelial cells
whats the blood flow throughout the udder
100 ml/s
is the lympathic system in the udder regulatory with the heart?
no because targeting to help with cow movement & cell proliferation
milk let down signalled by?
hormones signal NS by stimulus
HTM signals oxytocin from PTG, travels through blood to OTC receptors, takes 30s for milk letdown
Milk Accumulation occurs where
cistern hold milks but alveoli compartment holds >80% milk
What causes cell death in udder?
decreases as milk lactation goes on
& milk accumulation
why do cells die in udder?
exposed to a lot of oxidative stress
milk secretory cells synthesis increases or decreases with incr milking times?
increases
cell proliferation increases or decreases for next lactation phase with incr dry off period?
increases
Lactation Curve
undifferentiated cells > cell division > differential secretory cells > cell lose rate > death & reabsorption of secretory cells
how does the dry off period work for cell synthesis ?
cell synthesis in alveoli compartments with decrease as milking stops
what is shown with a longer dry off period in regards to cell life?
higher proliferation, less oxidative stress, replacement of old cells
