UC case study Flashcards
Mild UC flare up criteria
- Bowel movements = under 4
-Only small blood in stools
-
Moderate UC Flare up criteria
- 4-6 bowel movements per day
- mild - severe blood in stools
Severe flare up UC
- 6+ Bowel movements/day
-visable blood
+ 1 of:
- Pyrexia (37.5’+)
- pulse over 90
- Anaemic
- Erythrocyte sedimentation rate over 30mm/hour
What is Infliximab and when would it be given?
A biologic therapy with anti-TNF antibodies. Used in acute setting as rescue therapy for UC flare up patients who have failed IV steroids.
Why are stool samples taken for patients with IBD flare ups?
Because they can still have concurrent infective colitis.
What infection are UC patients at increased risk of contracting?
C. diff
Temp. indication for blood cultures to be taken?
Above 38
Tachycardia presentation, what scan?
ECG
Why wouldn’t TFT and Haematinics (active B12, anaemic assesment) be assessed in an an acute hospital flare up?
Hard to interpret
UC flare up, hosp admission, would you do a lactate?
Yes, helpful for prognostication and therapy success
Which inflam. markers present in IBD flare up?
High CRP, platelets, WCC
Low albumin
Anaemia
first line treatment for severe flare of Crohn’s or Ulcerative Colitis
IV methylprednisolone (Steroid), 30mg 2x/day.
100mg Hyrocortisone every 6h
DVT Prophylaxis
When are 5ASA in high doses (oral and topical) used?
Reserved for moderate/severe flare up
What are Thiopurine immunomodulators used for ?
exclusively for maintenance therapy as they take over 6 weeks to reach full effect.
USS abdomen is useful for assment of what ?
Solid Organ assesment
