UBP book 3 Flashcards
Aortic stenosis transvalvular gradients
<25: mild
25-40: moderate
40-50: severe
> 50: critical
Aortic stenosis, valve areas
Normal 2.5 to 4
Mild 1.5 to 2
Moderate 1 to 1.5
Severe .7 to 1
Critical less than 0.7
Aortic stenosis, velocity of aortic jets in meters per second
Mild less than three
Moderate 3 to 4
Severe 4 to 4.5
Critical greater than 4.5
When do you need prophylaxis for bacterial endocarditis?
- prosthetic, cardiac valve or prosthetic material used for valve repair
-Previous occurrence of infectious endocarditis
-Unrepaired cyanotic congenital heart disease
-Six month postoperatively following repaired congenital heart defect using prosthetic material
-Repaired congenital heart disease with residual defect
-Cardiac transplant, who develops valvulopathy
Went to discontinue enoxaparin to neuraxial
24 hours
Spinal and epidural, anesthesia,
In multiple sclerosis
Can be associated with an exacerbation of MS
-More significant and spinal and epidural, using high concentrations of local anesthetic, less likely with dilute solutions for labor pain control
When do you need to start taking a platelet level with heparin?
After four days for risk of heparin induced thrombocytopenia
How long to hold subq heparin before spinal
4-6 hours or normal PTT
How long to hold subcutaneous heparin with three times a day dosing at higher doses before spinal
12 Hours and normal PTT
Can you use protamine to reverse, low molecular weight heparin?
No
Asthmatic patients way to decrease ventricular rate
Diltiazem
symptoms of PDPH
-frontal-occipital HA
-Dec pain w/ laying flat
-N/V
-neck stiffness
-photophobia
-diplopia (stretching on abducens n)
-tinnitus, hearing loss
(Sz rare from cerebral vasospasm)
Aspiration ppx in pregnancy
Metochlopramide
Famotidine
Sodium citrate
Why do we give stress dose steroids?
Suppression of hypothalamic-pituitary adrenal axis with exogenous steroids -> cannot produce adequate cortisol under stress conditions
Symptoms of Addisonian crisis
(Life-threatening low cortisol)
-fever
-abd pain
-dehydration
-N/V
-hypoglycemia (cortisol promotes gluconeogenesis)
-acidosis
-hyperK, hypoNa (Dec Aldo)
-circulatory collapse
-depressed mentation
stress dose steroids
100mg IV hydrocoritsone preop
100mg q8h on day of surgery
epidural ok for c/s in pt w/ MS?
-acknowledge risk of exacerbating MS symptoms -> however lower with short duration of action local anesthetics
-benefits of avoiding manipulating difficult airway, red risk of aspiration, superior post op analgesia
succinylcholine and MS
AVOID -> likely to have chronic skeletal muscle weakness -> run the risk of hyperK
emergent c/s needs GA, severe AS induction?
-difficult airway equipment available
-premeds: asp ppx, albuterol, fluids for AS, consider esmolol to avoid tachycardia w/ laryngoscopy
-cadioversion pads (need atrial kick and sinus) and phenylephrine
-L uterine displacement
-etomidate and narcotics -> rapidly secure airway and tell neonatal team about narcotics
-a line as soon as possible if not present yet
**assess if can get succ w/ comorbidities
ST changes in aortic stenosis after induction, what to do?
-give vasoconstrictor if concern is dec in preload or afterload causing ischemia -> need to inc coronary perfusion
-if concern is LV function and need dec in afterload -> give nicardipine (causes arterial dilation with minimal venodilation -> won’t impact preload)
large PPH, what to do?
-verify pt receiving pitocin
-FiO2 100%, ensure hemodyanimc stability -> likely req phenyleprhine
-notify blood bank and call for pRBCs
-inc oxytocin
-methergine (semisynthetic ergot alkaloid), hemabate PG F2alpha analogue), or misoprostol (PG E1 analogue)
-OB: uterine massage -> IU balloon -> compression sutures -> ligate arteries -> hysterectomy
CI for methergine
HTN
coronary artery issues (causes coronary artery vasoconstriction)
pregnant pt w/ chorio and MS and ASA, 5 hours after pulling epidural, b/l leg weakness and back pain, ddx?
-bactermia from chorio
-epidural/spinal hematoma
-residual epidural blockade
-tissue damage w/ needle instrumentation
-relapsing MS
signs/symp w/ epidural/spinal hematoma
back pain or pressure: severe and unrelenting
-bowel/bladder dysfunction (urinary retention)
-radicular pain (shoots down into legs)
-sensory deficits
sign/symp w/ MS relapse
paresthesias
-weakness
-sensory deficits
-urinary incontinence, bowel retention
-visual and gait disturbances
-autonimic dysfunction
-vision changes
post c/s MS was on AC w/ epidural catheter, urinary incontinence w/ back pain and weakness, what to do?
-likely MS relapse HOWEVER spinal/epidural hemaotoma needs to be ruled out first
-examine pt -> determine if weakness progressive or recessive -> MRI and c/s neurosurgery
-intervention needs to occur w/i 6-12 hrs to avoid irreversible SC injruy
restart therapeutic enoxaparin after c/s?
-24 hours following surgery
AND
-at least 2 hours after epidural catheter removed
*acknowledge risk of DVT/PE v bleeding from surgery or epidural/spinal hematoma
post c/s dyspneic ddx w/ MS, AS, PEC?
-pulm thromboembolism, DVT, AFE
-HF
MI
bronchospasm
TPTX (PTx after central line)
pulm edema (PEC, AS)
aspiration
MS
PE immediately postop, tx?
-100% FiO2
-give inotropes and fluids using CVP, a line, TEE monitors -> pulm vasodilators (nitric oxide, milrinone [PDE inh])
-intubate and mechanically ventilate if needed
-avoid AC due to stop -> vena-cava filter, or pulm embolectomy
how does inhaled nitric oxide work?
inc cGMP -> dec in intracellular calcium and smooth m relaxation
2 days post c/s HA, ddx?
-tension HA
-migraines
-PDPH
-lactation HA
-PNEUMOCEPHALUS (if LOR done w/ air)
-PEC?
-SAH, SDH
PDPH, tx?
hydration
caffiene
abd binder (inc intraabd pressure)
pain control
**consider epidural blood patch, but look at AC likely postop
MVA cant move extremities, SOB, ddx?
-cervical spine injury above C6
-PTX
-pulm edema (tamponade, MI, PE, neurogenic pulm edema)
-PE (fat emoblism 2/2 long bone fx)
what is neurogenic pulm edema
head injury or cervical spinen injury -?> sympathetic activation -> systemic vasoconstriction -> dec LV compliance and inc LA pressure -> pulm edema
cardioaccelerator fibers
T1-T4
cervical SC injury, concerns?
-resp dysfunction (loss of diaphragmatic fxn)
-hypoTN (loss of sympathetic vascular tone and cardioaccelerator fibers
-pulm aspriation (impaired airway reflexes)
-thermal regulation (loss of vasoconstriction and temp sensation)
-arrhythmias (autonomic dysfunction)
-end organ ischemia (inc ICP, CAD< hypoTN, acidosis, hypoxia, anemia)
-difficult airway
hyperventilate w/ SC injury or TBI?
Nope
-head trauma and SC trauma -> dec SCBF and CBF 1st 24 hours -> concernerd for ischemia
R on T phenomenon
When a QRS from a PVC lands on a T wave during the refractory period
-or a shock is delivered on a T wave
**can cause V fib or V tach
When are PVCs a problem?
-frequent: more than 3 per minute
-occur in runs of 3 or more
-R on T pneomenon
-> all lead to inc risk of V tach or V fib
**more than 5-6 per minute -> inc periop morbidity
What causes PVCs?
hypoxemia
-MI, hypoK, hypoMg
-symp acctivation
-mechanical irritation (Central line)
-d/c drugs that prolong QT
-ensure defibrilator
What to do if pt hemodynamically unstable or symptomatic w/ PVCs?
overdrive pacing
antriarrhythmic: amiodarone, a beta blocker
**if unstable -> cardiovert, stable -> amio
Spinal shock
can occur following acute SC injury
-flaccid paralysis, paralytic ileus
-loss of sensation, spinal reflexes, symp vasomotor TONE!
-no otemp regulation below injury
-can get loss of diaphragmatic function, IC and m function (can’t clear pulm secretions), loss of cardioaccelerator fibers
**can last 1-3 weeks -> risk of resp dysfxn, hemodynamic instability, aspiration, DVT/PE, hypothermia
How long for inc in extrajunctional ACh receptors after SC injury?
24-48 hours
What to do if whole bottle of volatile spills on floor
-risk of significant expsoure of OR personnel
-suction spilled volatile into plastic container -> seal and labor -> transport to appropriate waste disposal site
-verify pt secured, ensure adequate sedation and NMB -> prepare for transport into different room
SC injury to C5 w/ CAD and DES -> when can have elective surgery?
-resolution of hemodyanmic stability 2/2 spinal scord shock?
-plavix can be safely d/c ideally 6 months after DES
What level does autonomic hyperreflexia occur above?
T7
O2 supply compromised what to do?
**concern for giving hypoxic gas mixture
-switch to backup O2 cylinders
-disconnect main pipeline supply
-hand ventilate w/ low gas flows -> if pneumatically driven vent uses more O2
-ask for additional E-cylinders
Estimating O2 E-cylinder supply time
O2 cylinder pressure (psig)/ (200 x oxygen flow rate in L/min)
Autonomic hyperreflexia, what to do?
-surgeon to stop
-deepen anesthesia
-vasodilator: NG, nitroprusside
-bladder empty
-a line
-monitor for complications: cerebral, retinal, SAH, sz, MI, dysrhtyhmias, pulm edema
Pathophys of autonomic hyperreflexia
pain below level of SC injury -> reflex sympathetic d/c -> not modulated by inhibitory impuses from CNS -> unopposed symp d/c -> vasoconstriction below level of lesion, and vasodilationn above lesion where can stimulate carotid sinus receptors -> reflex bradycardia
normal closure ducturs arteriosus
ventilation -> arterial O2 levels inc and PVR dec
-dec in PVR leads to a L to R PDA shunt -> exposure to blood with higher O2 count
-decrease in PG w/ separation from placenta -> closure
reasons PDA didn’t close
hypoxia at birth (no dec in PVR)
-prematurity: poorly contractile muscular layer in ductus artioersus -> didn’t appropriately contract w/ dec PG and inc in O2)
respiratory distress syndrome of the newborn reason?
premature infants and insufficient surfactant -> widespread atelectasis -> intrapulm shuting -> hypoxemia and acidosis
sympatoms of respiratory distress syndrome of the newborn
hypoxemia
acidosis
nasal flaring
accessory muscle use while breathing
tachypnea, tachycardia
b/l rales
cyanosis
ground glass infiltrates b/l on CXR