UA Diagnostics Flashcards
1
Q
When would you order a UA
A
- Flank pain, back pain, abdominal pain, painful or frequent urination, changes in urine color (blood)
- Part of wellness exam, new pregnancy evaluation
2
Q
Purpose of the UA
A
Detect:
- substances secreted in the urine reflecting metabolic disturbances
- ->Ex: glucose, nitrite, ketones
- Intrinsic renal conditions
- ->Ex: acute or chronic kidney dz, other dx’s resulting in the failure of the kidney to maintain homeostasis of body fluid volume and composition
3
Q
Types of Urine Specimens
A
- Random
- Catheter
- Midstream clean-catch
- First morning
- Fasting
- 2 hour post prandial
- Suprapubic puncture
- Pediatric bags
4
Q
Three components of UA
A
- Physical: color, transparency, odor, volume
- Chemical: protein, glucose, ketone, bilirubin, pH, blood, nitrite, leukocyte esterase, urobilinogen, specific gravity
- Microscopic (“formed elements”): WBC’s, RBCs, epithelial cells, casts, crystals, microorganisms
5
Q
How is a UA ordered?
A
- Dipstick UA: typical UA point of care diagnostic test
- Dipstick UA w/micro if indicated
- Complete UA (includes micro)
- Complete UA with relax urine culture: UA, micro eval, and culture
6
Q
Colored Urine Specimen and what it means
A
Straw: normal
Red: blood in the urine
Amber: Dehydrated
7
Q
Turbid Urine Specimens
A
=Cloudy samples
–>Cells, infection
8
Q
Reagent Strip/Dipstick Analysis
A
- Convenient and easy to use
- Requires strict compliance w/ directions to ensure analytical reliability
- DO NOT store in a refrigerator
- Avoid exposing reagent strips to moisture, fluorescence light, sunlight, heat, acids, alkalis,
- Do not touch test areas of reagent strip
9
Q
Leukocyte esterase
A
- WBC’s in the urine
- ->this is a marker for WBC’s
10
Q
Nitrites
A
- Most specific test on dipstick to identify infection!
- Convert nitrates to nitrites by bacteria (gram -)
11
Q
Most common cause of UTI’s
A
E. coli
12
Q
Urobilinogen
A
- RBC breakdown
- Indicative of hemolysis, bilirubin process
13
Q
Protein
A
- Reabsorption should be 100% by the kidneys, thus there should be NO protein in the urine (a.k.a Albumin)
- Filtering process in the kidney is breaking down= DM, HTN that lead to nephropathy/chronic kidney dz (CKD)
14
Q
pH
A
-Helps you assess if acidic or alkalotic
15
Q
Blood
A
- Should be no blood in the urine
- Kidney stones: nephrolithiasis
- Menstruation: contaminated sample
- Note: not actually detecting RBC’s
- ->enzymatic rxn when RBC’s are present in the urine