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PH2113 Disease & Drugs 1 > U3 L4 Autoimmunity > Flashcards

U3 L4 Autoimmunity Flashcards

1
Q

What is autoimmunity?

A

immune response directed against self antigens (auto antigens)

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2
Q

What factors can influence the presence of autoimmunity?

A
  • combination of susceptibility genes
  • external triggers e.g. environment, infections, trauma
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3
Q

How could autoimmune diseases be described?

A
  1. systemic (non-organ specific) or organ-specific
  2. involve adaptive immune system and mix of mechanisms from Type II, III, IV hypersensitivities
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4
Q

What percentage of the population are reported to have an autoimmune disease?

A

3-4%

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5
Q

What are the most common autoimmune diseases?

A
  1. overactive thyroid - Graves Disease
  2. underactive thyroid - Hashimoto’s Disease
  3. Pernicious anaemia - stomach
  4. Multiple Sclerosis - CNS
  5. Type 1 diabetes
  6. Rheumatoid arthritis - systemic
  7. SLE (systemic lupus)
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PH2113 Disease & Drugs 1 (5 decks)

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