Typhoid Fever Flashcards

1
Q
A
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2
Q

What is another name for typhoid fever?

A

Enteric fever

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3
Q

What type of illness is typhoid fever?

A

Potentially fatal multisystemic illness

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4
Q

What are the classic presentations of typhoid fever?

A
  • Fever
  • Malaise
  • Diffuse abdominal pain
  • Constipation
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5
Q

What long-term effects can survivors of typhoid fever experience?

A

Long-term or permanent neuropsychiatric manifestations

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6
Q

How have improved living conditions impacted typhoid fever in industrialized countries?

A

Drastically reduced morbidity and mortality

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7
Q

In which regions does typhoid fever remain a public health problem?

A
  • WHO African Region
  • Eastern Mediterranean Region
  • South-East Asia Region
  • Western Pacific Region
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8
Q

As of 2019, how many people worldwide are estimated to be affected by typhoid fever?

A

9 million people

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9
Q

How many people die yearly from typhoid fever as of 2019?

A

110,000 people

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10
Q

What is the primary causative agent of typhoid fever?

A

Salmonella enterica serotype typhi

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11
Q

Which other Salmonella serotypes are associated with typhoid fever, albeit to a lesser extent?

A
  • Salmonella enterica serotype paratyphi A
  • Salmonella enterica serotype paratyphi B
  • Salmonella enterica serotype paratyphi C
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12
Q

What family do Salmonella species belong to?

A

Enterobacteriaceae

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13
Q

True or False: Salmonella can produce a variety of gastrointestinal infections.

A

True

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14
Q

Fill in the blank: Typhoid fever is also known as _______.

A

enteric fever

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15
Q

What is the main causative organism of typhoid fever?

A

Salmonella typhi

Salmonella typhi is a human pathogen known for causing typhoid fever.

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16
Q

What type of bacteria is Salmonella?

A

Gram negative

Salmonella is classified as a Gram-negative bacterium.

17
Q

What is the shape of Salmonella bacteria?

A

Rod shaped

Salmonella has a rod-like shape characteristic of many bacteria.

18
Q

Is Salmonella facultative anaerobic or aerobic?

A

Facultative anaerobic

Salmonella can grow in both the presence and absence of oxygen.

19
Q

What is a key feature of Salmonella’s cell structure?

A

Polysaccharide layer

This layer contributes to the encapsulation of the bacteria.

20
Q

What type of metabolism does Salmonella utilize?

A

Respiratory fermentative metabolism

This type of metabolism allows Salmonella to produce ATP in different environments.

21
Q

What does a positive reaction on Triple Sugar Iron Agar indicate?

A

Black precipitate when hydrogen sulfide is produced

This indicates the production of hydrogen sulfide by Salmonella.

22
Q

What is the temperature range in which Salmonella can grow?

A

4°C - 36°C

This range allows Salmonella to survive in various environments.

23
Q

How long has Salmonella typhi been recognized as a human pathogen?

A

Almost 1000 years

This indicates the long history of Salmonella typhi affecting human health.

24
Q

What is the effect of boiling on Salmonella?

A

It is killed by boiling

Boiling water is an effective method to eliminate Salmonella.

25
What is the oxidase test result for Salmonella?
Oxidase negative ## Footnote This characteristic helps in differentiating Salmonella from other bacteria.
26
Does Salmonella have a non-human vector?
No, it has no non-human vector ## Footnote Salmonella typhi is primarily transmitted through human hosts.
27
What is the lowest pH at which Salmonella can survive?
As low as 1.5 ## Footnote This indicates Salmonella's resilience in acidic environments.
28
What does the name 'typhi' mean?
Derived from the Greek word 'typhos' meaning ethereal smoke or cloud ## Footnote This name reflects the historical perception of the disease.
29
Fill in the blank: Salmonella is _______ intracellular.
facultative ## Footnote This term describes Salmonella's ability to live both inside and outside host cells.
30