Types of DNA Damage and Mechanism of Repair Flashcards

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1
Q

Nicks in DNA strand

A

repaired by DNA ligase

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2
Q

Chemically modified base

A

Base excision (removal by base-specific DNA glycoysis)

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3
Q

Mismatched bases

A

Corrected by mismatched repair (excision and resynthesis)

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4
Q

Apurinic or apyrimidinic site

A

fixed by enonuclease repair system

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5
Q

Damaged region of DNA

A

Nucleotide excision repair (excision and repair across partner strand)

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6
Q

Pyrimidine dimers (from UV light)

A

Enzymatically reversed

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7
Q

Damaged region of DNA

A

DNA damage bypass (sequence in damaged region recovered via recombination)

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