Type II DM Flashcards
1
Q
Can insulin be used during surgery? Pregnancy?
A
Yes!
2
Q
Sulfonylurea Class Drug
A
Glimepiride
3
Q
Glimepiride MOA
A
Enhance secretion of insulin by beta cells; blocks ATP sensitive K+ channels
4
Q
Glimepiride Use
A
Decrease glucagon production
Increase tissue sensitivity to insulin
5
Q
Glimepiride PK
A
Orally absorbed
Protein bound
Metabolized by liver, excreted by kidneys
6
Q
Glimepiride dose
A
1x/day; take 30 mins before meal
7
Q
Glimepiride side effects
A
Hypoglycemia
Weight gain
8
Q
Glimepiride Contraindications
A
Liver or kidney disease