Type 2 Diabetes Flashcards
0
Q
Age of onset
A
Maturity onset > 40 years
1
Q
Prevalence
A
Very common in adults 90% of all cases
2
Q
Presentation
A
Gradual (months to years)
3
Q
Insulin?
A
Relative (insulin resistance)
4
Q
Physique
A
Often obese (central obesity)
5
Q
Islets
A
Near normal appearance
6
Q
Ketosis
A
Can occur (HONK coma)
7
Q
Etiology
A
Strong genetic component aggravated by obesity
Gene defects of the b-cell secretory apparatus(glucokinase and sulphonylurea receptor SUR)
Thrifty gene-link with low birth weight.
Part of the metabolic syndrome