Type 2 Diabetes Flashcards

0
Q

Age of onset

A

Maturity onset > 40 years

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1
Q

Prevalence

A

Very common in adults 90% of all cases

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2
Q

Presentation

A

Gradual (months to years)

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3
Q

Insulin?

A

Relative (insulin resistance)

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4
Q

Physique

A

Often obese (central obesity)

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5
Q

Islets

A

Near normal appearance

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6
Q

Ketosis

A

Can occur (HONK coma)

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7
Q

Etiology

A

Strong genetic component aggravated by obesity
Gene defects of the b-cell secretory apparatus(glucokinase and sulphonylurea receptor SUR)
Thrifty gene-link with low birth weight.
Part of the metabolic syndrome

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