Type 2 Diabetes

Question 1

What is the first-line pharmacological treatment for Type 2 diabetes according to NICE CKS?

Answer 1

Metformin

Question 2

True or False: Sulfonylureas are recommended as the first-line treatment for Type 2 diabetes.

Answer 2

False

Question 3

Fill in the blank: The primary mechanism of action of Metformin is to decrease __________ production in the liver.

Answer 3

glucose

Question 4

Which class of medications is used to stimulate insulin secretion in Type 2 diabetes?

Answer 4

Sulfonylureas

Question 5

What is the maximum daily dose of Metformin for adults?

Answer 5

2,000 mg

Question 6

True or False: DPP-4 inhibitors can lead to weight gain in patients with Type 2 diabetes.

Answer 6

False

Question 7

What is the role of SGLT2 inhibitors in the management of Type 2 diabetes?

Answer 7

To promote renal glucose excretion

Question 8

Name one common side effect of Metformin.

Answer 8

Gastrointestinal disturbances

Question 9

What is the primary benefit of using GLP-1 receptor agonists in Type 2 diabetes treatment?

Answer 9

Weight loss

Question 10

Which medication class is contraindicated in patients with a history of pancreatitis?

Answer 10

DPP-4 inhibitors

Question 11

Fill in the blank: Insulin therapy may be initiated in Type 2 diabetes when __________ control is inadequate.

Answer 11

glycemic

Question 12

What is the potential cardiovascular benefit of SGLT2 inhibitors?

Answer 12

Reduction in heart failure risk

Question 13

True or False: Thiazolidinediones are a first-line treatment option for Type 2 diabetes.

Answer 13

False

Question 14

Name one contraindication for using Metformin.

Answer 14

Severe renal impairment

Question 15

What is the target HbA1c level for most adults with Type 2 diabetes?

Answer 15

Below 48 mmol/mol (6.5%)

Question 16

Which medication class is associated with a risk of hypoglycemia?

Answer 16

Sulfonylureas

Question 17

Fill in the blank: The addition of __________ is recommended when Metformin alone is insufficient for glycemic control.

Answer 17

another antidiabetic medication

Question 18

What should be monitored regularly in patients taking Metformin?

Answer 18

Renal function

Question 19

True or False: Lifestyle changes should be encouraged alongside pharmacological management in Type 2 diabetes.

Answer 19

True

Question 20

What is one of the main actions of GLP-1 receptor agonists?

Answer 20

Increase insulin secretion in response to meals

Question 21

Which medication can be used as a second-line treatment if Metformin is not tolerated?

Answer 21

DPP-4 inhibitors

Question 22

Fill in the blank: SGLT2 inhibitors can cause __________ as a side effect.

Answer 22

genital infections

Question 23

What is the role of insulin in the management of Type 2 diabetes?

Answer 23

To lower blood glucose levels

Question 24

What is a common starting dose for DPP-4 inhibitors?

Answer 24

100 mg once daily

Question 25

True or False: Weight loss is not a concern when prescribing antidiabetic medications.

Answer 25

False

Question 26

What lifestyle modification is essential for managing Type 2 diabetes?

Answer 26

Dietary changes and physical activity

Question 27

What is the function of thiazolidinediones in Type 2 diabetes management?

Answer 27

Improve insulin sensitivity