Tutorial 1

Question 1

An antigen is

Answer 1

Any agent that can specifically bind to components of the immune response

Question 2

An immunogen is

Answer 2

Any agent capable of inducing an immune response

• all immunogens are antigens, not all antigens are immunogens

Question 3

Haptens are

Answer 3

Low molecular weight molecules that do not induce an immune response alone, but can induce a response when coupled with a larger molecule

Question 4

Immunogenicity is

Answer 4

Affected by foreigners, molecular size and chemical complexity

Question 5

Proteins make good immunogens provided they are

Answer 5

Complex and large enough

Question 6

Two poor immunogens

Answer 6

Lipids and nuclei acids (unless conjugated to proteins

Question 7

Immunogenic responses occur

Answer 7

To specific structures (termed epitomes)

Question 8

MHC I antigen processing is associated with

Answer 8

Endogenous route of antigen processing

Question 9

MHC II antigen processing is associated with

Answer 9

• Exogenous route of antigen processing
• Activation of CD4 cells
• Antigen processing via an endosome-phagolysosome vacuole

Question 10

An anamnestic immune response may also be termed as a

Answer 10

Secondary immune response

Question 11

Freund’s complete suspension is characterised by

Answer 11

• Being an adjuvant
• ConTaining mycobacterial components
• Is suspended in a mix of oil and water

Question 12

Neutrophils, macrophages and eosinophils are all derived from the

Answer 12

Myeloid cell line

Question 13

Dendritic cells are the most important antigen presenting cell (APC) that initiates T cell responses to

Answer 13

Protein antigens

Question 14

Natural killer cells are characterised by

Answer 14

An inactivating receptor responsive to MHC1 cells

Question 15

A Kupffer cell is best described as a

Answer 15

Macrophage resident in the liver