Tushar 1.4 Flashcards
What is passive transport
high to low conc No ATP includes: - diffusion - facilitated diffusion - osmosis relies on kinetic energy
What is simple diffusion
passive net movement of particles from high concentration to low concentration
Small + non-polar things w no charge diffuse easily across membrane
What is facilitated diffusion
Passive movement from high to low concentration across cell membrane via the aid of a membrane protein
For large polar substances/ions
Membrane protein is specific
2 types of transport facilitated diffusion proteins
Channel
Carrier
Carrier and channel proteins
Carrier proteins
- change shape
- specific
- also does active transport
- slower
Channel proteins
- have pore for ions to cross (no change shape)
- selective
- cant do active transport
- faster
What is osmosis
net movement of water particles across a semi-permeable membrane from a region of low solute conc (high water potential) to a region of high solute conc (low water potential) till equilibrium
Which molecules don’t affect osmolarity
insoluble
What is osmolarity
measure of solute concentration
hypertonic, hypotonic, isotonic
hypertonic: relatively higher osmolarity
hypotonic: relatively lower osmolarity
isotonic: solutions w same osmolarity
What is active transport
Movement of substances against conc gradient
Uses ATP
Needs protein pumps that change shape
Sodium-potassium pump
1) 3 sodium ions bind to binding site of pump
2) phosphate group transferred to pump via hydrolysis of ATP
3) this causes protein pump to change shape, moving 3 sodium ions out of cell
4) Now 2 potassium ions on the extracellular side bind to the pump
5) phosphate group is released, pump returns to original shape
6) Change in shape moves potassium ions into the cell
endocytosis and exocytosis
- needs energy
- cell membrane can break and reform, it is fluid and flexible
- for larger molecules
endocytosis
- for large to enter the cell
- Cell membrane moves inwards to surround the molecule
- molecule is sealed in a vesicle
- vesicle moves into the cell
- phagocytosis: uptake of solid substances
- pinocytosis: uptake of fluids
Exocytosis
- for large substances to exit cell
- vesicle fuse with membrane, expelling contents extracellular environment
- this replaces phospholipids lost by endocytosis