Tumours of the oesophagus and stomach Flashcards
Name two types of oesophageal cancer?
Adenocarcinoma
Squamous Cell Carcinoma
Which type of cancer can Barrett’s oesophagus predispose?
Oesophageal adenocarcinoma
What are the signs and symptoms of oesophageal cancer?
Dysphagia Odynophagia Upper GI bleed Anaemia Weight loss
What organism can cause gastric adenocarcinoma?
H. Pylori
What does GIST stand for?
Gastro-intestinal Stromal Tumour
What are the signs and symptoms of gastric cancer?
Dyspepsia Upper GI bleed Anaemia Weight loss Abdominal mass Anoreixa/ early satiety Vomiting
What is the potentially curative treatment of oesophageal cancer?
Surgery (with or without N-Acetyl Cysteine)
or
Radical chemotherapy
What are the options for palliative treatment of oesophageal cancer?
Chemotherapy
Radiotherapy
Stenting
How can you accurately stage oesophageal cancer?
CT Thorax/Abdomen
CT/PET, EUS, Laparoscopy
(Search hard for metastatic disease)
What is the potentially curative treatment for gastric cancer?
Surgery (with ot without N-Acetyl Cysteine)
only potentially curative option
What does NAC stand for?
N-Acetyl Cysteine
What are the options for palliative treatment of gastric cancer?
Chemotherapy
Radiotherapy
How can you accurately stage gastric cancer?
CT Thorax/Abdomen
Laparoscopy
(Search hard for metastatic disease)
What is the rate if 5 year survival for a patient with oesophageal cancer?
11%
What is the rate of 5 year survival for a patient with gastric cancer?
15%
What factors negatively effect the prognosis of a patient with oesophageal cancer?
Oesophageal obstruction
Tumour longer than 5cm
Metastatic disease
What factors negatively effect the prognosis of a patient with gastric cancer?
Metastatic disease Short history Advanced age Proximal lesion Locally advanced lesion (Superfical gross appearance) - (linitis plastica)
