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Pathology FRCS > Tumours > Flashcards

Tumours Flashcards

1
Q

Soft Tissue Sarcomas with LYMPH node Mets

A 
ESARC
Epithelioid sarcoma
Synovial sarcoma
Angiosarcoma
Rhabdomyosarcoma
Clear cell sarcoma
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2
Q

What are the radiographic findings of non ossifying fibroma (NOF)?

A

metaphyseal eccentric “bubbly” lytic lesion surrounded by sclerotic rim
cortex may be thin + expanded
length > width
as bone grows - lesion migrates to diaphysis

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3
Q

What are the histological findings for NOF?

A

fibroblastic spindle cells in whirled pattern with haemosiderin pigmentation + numerous giant cells

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4
Q

Diaphyseal tumours

A 
AEIOUY
A= Adamantinoma
E= Eosinophilic granuloma (the great mimicker)
I= Infection
O= Osteoid osteoma/osteoblastoma
U= Ewings
Y= mYeloma, lYmphoma, fibrous dYsplasia
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5
Q

Diaphyseal tumours (by age)

A

<10 yrs: Eosinophilic granuloma

teenager: Ewing’s
adult: Lymphoma

> 60yrs: Mets/lymphoma

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6
Q

Mx of primary Bone Tumours

A

As easy as 1, 2, 3
1 - chondrosarcoma - surgery
2 - osteosarcoma - chemo + surgery
3 - Ewing’s - neo-adjuvant chemo, surgery + radiotherapy

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7
Q

Giant Cell Tumour - Radiology

A 
Epiphyseal
Eccentric
Lucent
Expanded
"soap bubbles"
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8
Q

Questions to ask when imaging bone tumours

A
  1. pt age
  2. which bone?
  3. Where in bone
  4. what is the lesion doing to the bone
  5. how is the bone responding?
  6. Is there periosteal reaction?
  7. Is there an associated soft tissue mass?
  8. I there a characteristic matrix?
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9
Q

Tumours of the Epiphysis/apophysis

A

The 4 horsemen of the apophysis:
Chondrosarcoma

GCT

ABC - only benign tumour that crosses physis

Clear cell chondrosarcoma

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10
Q

Well-defined OSTEOLYTIC lesions

A 
FEGNOMASHIC
Fibrous dyslasia
Eosinophilic granuloma / encondroma
GCT
NOF
Osteoblastoma
Mets / Myeloma
ABC
SBC
Hyperparathyroidism
Infection
Chondroblastoma / CMF
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11
Q

Well-defined OSTEOLYTIC lesions based on age

A

<10 yrs: EG/ SBC

10-20: NOF, osteoblastoma
fibrous dyslasia, EG
SBC/ABC
chondroblastoma / CMF

20-40: GCT
enchondroma
chondrosarcoma (low grade)
HPT (Brown tumour)
Osteoblastoma

> 40 Mets, myeloma, geode

ALL AGES: INFECTION

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12
Q

tumours found centrally in long bones

A 
SBC
EG
fibrous dysplasia
ABC
enchondroma
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13
Q

tumours for ECcentrically in long bones

A 
osteosarcoma
NO
chondroblastoma
CMF
GCT
osteoblastoma
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14
Q

Cortical tumours

A

osteoid osteoma

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15
Q

Juxtacortical tumours

A

osteochondroma

parosteal osteosarcoma

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Pathology FRCS (2 decks)

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