Tumour suppressor assosciated genes Cancers Flashcards

1
Q

Rb1

A

Retinoblastoma

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2
Q

p53

A

Li Fraumeni syndrome

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3
Q

WT 1

A

Wilms tumour

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4
Q

BRCA 1

BRCA 2

A

Famlial Breast Cancer

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5
Q

NF 1

A

Neurofibromatosis 1

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6
Q

NF 2

A

Neurofibromatosis 2

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7
Q

VHL

A

Von Hippel Lindau syndrome

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8
Q

INK4a

A

Melanoma

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9
Q

DCC

A

Colon cancer

DCC : Deleted in Colon Ca

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10
Q

APC

A

Colon cancer

APC : Adenomatous Polyposis Coli

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11
Q

MLH 1
MSH 2
MSH 6

A

Colon Ca

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12
Q

DPC

A

Pancreatic Ca

DPC : Deleted in Pancreatic Ca

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13
Q

PTCH

A

Gorlin syndrome

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14
Q

PTEN

A

Cowden syndrome

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15
Q

SMAD 2

SMAD 4

A

Juvenile Polyposis

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16
Q

CDNK2A

A

Familial Melanoma

17
Q

STK11

A

Peutz Jeghar syndrome

18
Q

CDH 1

A

Familial Gastric Ca