Tumour Pathology 1

Question 1

What is a tumour and characteristics?

Answer 1

An abnormal growing mass of tissue, growth is uncoordinated with surrounding tissue, growth continues after removal of stimulus that may have caused tumour, an irreversible change.

Question 2

What are the two groups of tumours?

Answer 2

Benign and malignant

Question 3

What is the fundamental property of cancer?

Answer 3

Its ability to invade into adjacent tissue and to metastasise and grow at other sites within the body.

Question 4

Why do we classify tumours?

Answer 4

Important for understanding tumour behaviour and for determining outcome and selecting therapy.

Question 5

What is classification of tumours based on?

Answer 5

Based on tissue of origin and whether it is benign or malignant.

Question 6

What would be the nomenclature for a benign glandular tumour?

Answer 6

Adenoma

Question 7

What would be the nomenclature for a benign squamous tumour?

Answer 7

Squamous papilloma

Question 8

What would be the nomenclature for a malignant glandular tumour?

Answer 8

Adeno-carcinoma

Question 9

What would be the nomenclature for a malignant squamous tumour?

Answer 9

Squamous carcinoma

Question 10

What is the suffix for tumours which are malignant?

Answer 10

-oma

Question 11

What is the suffix for a tumour which is malignant and in connective tissue?

Answer 11

-sarcoma

Question 12

What is the suffix for a tumour which is malignant and in epithelium?

Answer 12

-carcinoma

Question 13

What would be the nomenclature for a malignant bone tumour?

Answer 13

Osteo-sarcoma

Question 14

What would be the nomenclature for a benign fat tumour?

Answer 14

Lipoma

Question 15

What would be the nomenclature for a malignant white blood cell tumour?

Answer 15

Leukaemia

Question 16

What would be the nomenclature for a malignant lymphoid tissue tumour?

Answer 16

Lymphoma

Question 17

What would be the nomenclature for A) a benign melanocyte tumour and B) a malignant melanocyte tumour?

Answer 17

A) naevus B) melanoma

Question 18

What would be the nomenclature for a tumour of A) the CNS and B) the PNS?

Answer 18

A) astrocytoma B) schwannoma

Question 19

What would be the nomenclature for a germ cell tumour?

Answer 19

Teratoma

Question 20

Which teratomas are usually malignant?

Answer 20

Testicular teratomas

Question 21

What are the features of a benign tumour?

Answer 21

Non-invasive growth pattern, usually encapsulated, no evidence of invasion, no metastases, cells similar to normal, ‘well-differentiated’, functions similar to normal tissue, rarely causes death.

Question 22

What are the features of a malignant tumour?

Answer 22

Invasive growth pattern, no capsule or the capsule has been breached by tumour cells, cells abnormal, ‘poorly differentiated’, loss of normal function, evidence of spread of cancer, frequently cause death.