Tumour Markers Flashcards

1
Q

What are the cell-surface glycoprotein tumour markers?

A

Carcinoembryonic antigen (CEA)

CA125

CA19.9

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2
Q

What are the oncofetal protein tumour markers?

A

Human chorionic gonadotrophin (HCG)

Alpha-fetoprotein (aFP)

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3
Q

Tumour marker CA 125 is generally associated with which cancer?

A) Breast
B) Ovarian
C) Pancreatic
D) Prostate

A

B) Ovarian

CA 125 is a monoclonal antibody and is largely associated with ovarian cancer

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4
Q

Tumour marker CA 19-9 is generally associated with which cancer?

A) Breast
B) Ovarian
C) Pancreatic
D) Prostate

A

C) Pancreatic

CA 19-9 is a monoclonal antibody and is largely associated with pancreatic cancer

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5
Q

Tumour marker CA 15-3 is generally associated with which cancer?

A) Breast
B) Ovarian
C) Pancreatic
D) Prostate

A

A) Breast

CA 15-3 is a monoclonal antibody and is largely associated with breast cancer

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6
Q

Which tumour antigen is associated with prostatic carcinoma?

A

Prostate specific antigen (PSA)

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7
Q

Which tumour antigen is associated with hepatocellular carcinoma?

A

Alpha-fetoprotein (AFP)

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8
Q

Which tumour antigen is associated with teratoma?

A

Alpha-fetoprotein (AFP)

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9
Q

Which tumour antigen is associated with melanoma?

A

S-100

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10
Q

Which tumour antigen is associated with colorectal cancer?

A

Carcinoembryonic antigen (CEA)

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11
Q

Which tumour antigen is associated with schwannomas?

A

S-100

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12
Q

Which tumour antigen is associated with small cell lung carcinoma?

A

Bombesin

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13
Q

Which tumour antigen is associated with gastric cancer?

A

Bombesin

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14
Q

Which tumour antigen is associated with neuroblastoma?

A

Bombesin

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15
Q

True or false: Papillary thyroid cancer will cause a rise in calcitonin.

A

False

Medullary thyroid cancer will cause a rise in calcitonin levels, and is the only thyroid that will do this. This is because it originates in the parafollicular cells, which produce calcitonin.

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