Tumour Markers Flashcards
What are the cell-surface glycoprotein tumour markers?
Carcinoembryonic antigen (CEA)
CA125
CA19.9
What are the oncofetal protein tumour markers?
Human chorionic gonadotrophin (HCG)
Alpha-fetoprotein (aFP)
Tumour marker CA 125 is generally associated with which cancer?
A) Breast
B) Ovarian
C) Pancreatic
D) Prostate
B) Ovarian
CA 125 is a monoclonal antibody and is largely associated with ovarian cancer
Tumour marker CA 19-9 is generally associated with which cancer?
A) Breast
B) Ovarian
C) Pancreatic
D) Prostate
C) Pancreatic
CA 19-9 is a monoclonal antibody and is largely associated with pancreatic cancer
Tumour marker CA 15-3 is generally associated with which cancer?
A) Breast
B) Ovarian
C) Pancreatic
D) Prostate
A) Breast
CA 15-3 is a monoclonal antibody and is largely associated with breast cancer
Which tumour antigen is associated with prostatic carcinoma?
Prostate specific antigen (PSA)
Which tumour antigen is associated with hepatocellular carcinoma?
Alpha-fetoprotein (AFP)
Which tumour antigen is associated with teratoma?
Alpha-fetoprotein (AFP)
Which tumour antigen is associated with melanoma?
S-100
Which tumour antigen is associated with colorectal cancer?
Carcinoembryonic antigen (CEA)
Which tumour antigen is associated with schwannomas?
S-100
Which tumour antigen is associated with small cell lung carcinoma?
Bombesin
Which tumour antigen is associated with gastric cancer?
Bombesin
Which tumour antigen is associated with neuroblastoma?
Bombesin
True or false: Papillary thyroid cancer will cause a rise in calcitonin.
False
Medullary thyroid cancer will cause a rise in calcitonin levels, and is the only thyroid that will do this. This is because it originates in the parafollicular cells, which produce calcitonin.