Tumour Markers

Question 1

What is alpha feta protein relevant to

Answer 1

Germ cell/testicular cancers

Hepatocellular cancers

Question 2

What is alpha feta protein used for

Answer 2

Diagnosis
Monitoring treatment
Detecting reoccurrence

Question 3

What other cancers can AFP be associated with

Answer 3

Colorectal
Gastric
Hepatobilary
Lung

Question 4

What benign conditions can AFP be associated with

Answer 4

Cirrhosis
Pregnancy
Neural tube defects

Question 5

Which marker is used for hepatocellular, germ cell and testicular cancers

Answer 5

Alpha feta protein

Question 6

What cancer is calcitonin a tumour marker for

Answer 6

Medullary thyroid cancer

Calcitonin produced in the c cells of the thyroid

Question 7

What is calcitonin used for

Answer 7

Diagnosis, monitoring treatment, detecting reoccurrence

Question 8

What other associated cancers is calcitonin associated with

Answer 8

None known

Question 9

What associated benign conditions are associated with calcitonin

Answer 9

C cell hyperplasia

Question 10

What marker is used in medullary thyroid cancer

Answer 10

Calcitonin

Question 11

What tumour marker CA125 used in

Answer 11

Ovarian cancer

Question 12

What is the CA125 used for in ovarian cancer

Answer 12

Monitoring ovarian cancer

Prognosis after chemotherapy

Question 13

What other associated cancers to CA125 are there

Answer 13

Breast
Cervical
Endometrial 
Hepatocellular 
Lung
Non-Hodgkins lymphoma
Pancreatic
Medullary thyroid 
Peritoneal
Uterine

Question 14

What associated benign conditions are there with tumour marker CA125

Answer 14

Liver disease
Cystic fibrosis
Pancreatitis
Urinary retention
Diabetes
Heart failure
Pregnancy 
SLE
sarcoid
RA
Diverticulitis 
IBS
Endometriosis
Fibroids

Question 15

What tumour marker is associated with ovarian cancer

Answer 15

CA125

Question 16

What cancer is CA19-9 associated with

Answer 16

Pancreatic cancer

Question 17

What can tumour marker CA19-9 be used for

Answer 17

Monitoring pancreatic cancer

Question 18

What other cancers can be associated with Ca19-9

Answer 18

Colorectal 
Gastric 
Hepatocellular 
Oesophageal 
Ovarian

Question 19

What associated benign conditions are there to tumour marker CA19-9

Answer 19

Acute cholangitis
Cholestasis
Pancreatitis
Diabetes
IBS
Jaundice

Question 20

What is CA15-3 associated with

Answer 20

Breast cancer

Question 21

What is CA15-3 used for

Answer 21

Monitoring breast cancer

Question 22

What other cancers can tumour marker CA 15-3 be associated with

Answer 22

Hepatocellular

Pancreatic

Question 23

What associated benign conditions are associated with CA15-3

Answer 23

Cirrhosis
Benign breast disease
Normal health

Question 24

What is the tumour marker associated with breast cancer

Answer 24

CA 15-3

Question 25

What is carcinoembryonic antigen associated with

Answer 25

Colorectal cancer

Question 26

What can CEA be used for

Answer 26

Monitoring adenocarcinima

Question 27

What other cancers are associated with CEA

Answer 27

``` Breast Lung Gastric Mesothelioma Oesophageal Pancreatic ```

Question 28

What associated benign conditions are associated with CEA

Answer 28

``` Smoking Chronic liver disease Chronic kidney disease Diverticulitis Jaundice ```

Question 29

What tumour marker is associated with colorectal cancer

Answer 29

CEA carcinoembryonic antigen

Question 30

What is human chorionic gonadotropin (hCG) associated with

Answer 30

Germ cell/testicular | Gestational trophoblastic

Question 31

What can hCG be used for

Answer 31

Diagnosis Prognosis Monitoring treatment of germ cell tumours

Question 32

What other cancers are associated with hCG

Answer 32

Lung

Question 33

What other associated benign conditions are associated with hCG

Answer 33

Pregnancy

Question 34

What tumour marker is hCG associated with

Answer 34

Germ cell tumour Testicular Gestational trophoblastic

Question 35

What cancer are paraprotein associated with

Answer 35

Myeloma

Question 36

What can the tumour marker paraprotein be used for

Answer 36

Diagnosis Monitoring treatment Detecting reoccurrence

Question 37

What other cancers are associated with paraprotein

Answer 37

None known

Question 38

What benign conditions are associated with paraprotein

Answer 38

None known

Question 39

What tumour marker is myeloma associated with

Answer 39

Paraprotein

Question 40

What tumour is thyroglobulin a tumour marker for

Answer 40

Thyroid Follicular Papillary

Question 41

What can thyroglobulin be used for

Answer 41

Monitoring treatment | Detecting reoccurrence

Question 42

What other cancers are associated with thyroglobulin

Answer 42

None known

Question 43

What benign conditions are associated with thyroglobulin

Answer 43

None known