Tumors of Chest Wall Flashcards

1
Q

What % of primary chest wall tumors are malignant?

A

60%

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2
Q

What are the two types of chest wall tumors?

A

Bony/cartilaginous tumors and soft tissue tumors

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3
Q

T/F: 75% of primary chest wall tumors are painless?

A

TRUE

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4
Q

What imaging study is the most useful in evaluation of chest wall tumors?

A

CT scan

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5
Q

What is the tissue of origin for desmoid tumors?

A

Fibroblasts of deep muscle and connective tissue

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6
Q

T/F: Chest wall is the most common extraabdominal site for desmoid tumors?

A

TRUE

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7
Q

What is the primary treatment for desmoid tumors of the chest wall?

A

Wide local exicision, 4 cm margins

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8
Q

What are the indications for treatment of hemangioma or lymphangiomas

A

cosmetic regions, bleeding, ulceration

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9
Q

What are the typical demographics of malignant fibrous histiocytomas?

A

Male, 50’s-70s

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10
Q

What is the primary treatment for malignant fibrous histiocytoma?

A

Wide local excision

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11
Q

What is the primary treatment for rhabdomyosarcoma?

A

Wide local excision and chemo

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12
Q

What is the most common location for fibrous dysplasia in the chest?

A

Posterior or lateral aspect of ribs

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13
Q

What are the typical radiographic characteristics of fibrous dysplasia?

A

Ground-glass appearance in central area of rib

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14
Q

What are the typical radiographic characteristics of osteochondroma?

A

Pedunculated protuberance with intact cortex and stippled calcification in area of tumor

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15
Q

What is the chromosomal abnormality of Ewing sarcoma?

A

Translocation between chromosomes 11 and 22

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16
Q

What are the demographic characteristics of Ewing sarcoma?

A

Ages 10-15, males

17
Q

What are the characteristic radiographic findings of Ewing sarcoma?

A

Onion peel appearance

18
Q

What is the typical lab finding in osteogenic sarcoma?

A

Elevated alkaline phosphatase

19
Q

What are the classic radiographic findings of osteogenic sarcomas?

A

Sunburst pattern, Codman’s triangle

20
Q

What is the mutation associated with osteogenic sarcoma?

A

RB gene p53

21
Q

What is the primary site of metastases for patients with osteogenic sarcoma?

A

Lung

22
Q

What is the most common malignancy of the anterior chest wall?

A

Chondrosarcoma

23
Q

What chest wall malignancy has been associated with trauma?

A

Chondrosarcoma

24
Q

What are the radiographic findings of chondrosarcoma?

A

Mixed lytic and sclerotic pattern

25
Q

What chest wall malignancy has been associated with multiple myeloma

A

Plasmocytoma

26
Q

What lab findgs are associated with plasmocytoma?

A

Bence-jones proteinuria, hypercalcemia, abnormal protein elecrophoresis