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Tumors Flashcards

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1
Q

location of osteiod Osteoma

A

50% in tib/fib,
spine,
posterior elements

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2
Q

Age of osteiod Osteoma

A

2nd , 3rd decace

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3
Q

Clinical osteiod Osteoma

A

pain worst at night
relieved with salicylates 6-24 months before diagnosis
painful scoliosis
If intraarticular it may mimic JRA w/synovitis and joint effusion

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4
Q

Radiology findings of osteiod Osteoma

A

Reactive sclerosis
lucent nidus less than 1cm
may have central calcification
misleading MR

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5
Q

Tx for osteiod Osteoma

A

surgical radiofrequency ablation

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6
Q

Location of osteoblastoma

A

long bones 40% in sline

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7
Q

age osteoblastoma

A

2nd , 3rd decade

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8
Q

clinical findings of osteoblastoma

A

rarely agressive

pseudomalignant

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9
Q

Radiology osteoblastoma

A 
Giant Osteiod osteoma 
lucent nidus greater than 1.5 cm 
may have multiple internal calcifications 
maybe expansile 
less reactive sclerosis than OO
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10
Q

Location for osteosarcoma: classic medullary

A

medullary metaphyseal
40% femur
>50% at knee

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11
Q

age of osteosarcoma: classic medullary

A

10-25 yo

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12
Q

clinical findings of osteosarcoma: classic medullary

A

pain months before diagnosis

Elevated alkaline phosphate

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13
Q

Radiology findings of osteosarcoma: classic medullary

A

cloud like dense bone formation
may have extraosseous mass
sunburst
speculated periosteal reactive often with codman’s triangle

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14
Q

tx for osteosarcoma: classic medullary

A

poor prognosis (30% 5 yr) if presents with skip lesion of 4 lung mets ; isolated lesion 75% 5 yr survival

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15
Q

location of parosteal osteosarcoma

A

2/3 distal femoral metaphysis

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16
Q

age of parosteal osteosarcoma

A

27 YO , 5-10 years older than medullary

female >male

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17
Q

clinical findings for parosteal osteosarcoma

A

mass w/dull aching pain

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18
Q

radiology findings of parosteal osteosarcoma

A

amoprphous

cloud of mineralization in lobulated surface mass

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19
Q

Tx for parosteal osteosarcoma

A 
better prognosis than medullary
5 yr survival >90%
low grade 
chemo not indicated 
Best prognosis if no medullary extension
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20
Q

age for periosteal osteosarcoma

A

diaphysis

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21
Q

age for periosteal osteosarcoma

A

same age as medullary

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22
Q

clinical findings for periosteal osteosarcoma

A

1-2% of OS

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23
Q

Radiology findings of periosteal osteosarcoma

A

rare surface lesion
Periosteal reaction
soft tissue mass

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24
Q

tx for periosteal osteosarcoma

A

slightly better prognosis than medullary

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25
clinical findings for Telengiectatic osteosarcoma
5% of OS
26
Radiology findings of Telengiectatic osteosarcoma
Usually osteolytic frequent fluid filled levels spider web blood vessels so blood inside the bone
27
Tx for Telengiectatic osteosarcoma
prognosis same as classicl OS
28
clinical findings in osteosarcoma in paget's dz
occurs in 1% of paget pts rule of 1 classic finding: their hat wont fir anymore
29
tx for Telengiectatic osteosarcoma
poor prognosis 5 yr survival 3-8%
30
location of Endchondroma
50% in hands and feet | also long flat bones
31
age of Endchondroma
wide age range
32
clnical findings of Endchondroma
painless unless fx or malignant change Ollier's: multiple enchondromatosis usually presents as a growth disturbance in childhoold , not inherited 30% malignant tranformation Mafucci's multiple enchondromas w/soft tissue hemangiomas , all pts will die of cancer
33
radiology findings of Endchondroma
benign, intramedullary cartilaginous lesion, geographic lesion w/punchtate calcified matriz maycause scalloping or expansion
34
location of Juxtacortical chondroma
most in small tubular bones of hands & feet
35
age of Juxtacortical chondroma
usuallypain and swelling soft mass (50% calcify)
36
radiology finding of Juxtacortical chondroma
solid , benign cartilage tumor that can erode underlying bone , erosion and saucerization of underlying bone
37
location of chondroblastoma
Epiphysisi
38
age of chondroblastoma
2nd, 3rd decade
39
clinical findings of chondroblastoma
benign | pain and joint effusion
40
radiology findings of chondroblastoma
usually geographic, 50% have calcifications
41
location of chondromyxoid fibroma
76% in LE metaphysis
42
age of chondromyxoid fibroma
wide range most in 2nd decade
43
clinical findings of chondromyxoid fibroma
``` very rare (1% bone tumores) vague pain ```
44
Radiology findigns of chondromyxoid fibroma
multiloculated geographic with sclerotic margins no calcifications
45
location of Osteochondroma
metaphysis | points away from joint
46
age of Osteochondroma
usually adolelscence
47
clinical findigns of Osteochondroma
``` common decreased ROM malignat degenration suspect when growth afer skeletal maturity or pain ,cartilage cao > 2cm in adults ir 3 cm in children multiple hereditary ostechondromatosis, multiple exostoses autosomal dominant incomplete penetrance ```
48
Radiology findings of Osteochondroma
cartilage capped bony excrescence ( like bony exostosis ) | cap may calcify
49
age for Bizarre parosteal osteochondromatosis (Nora's lesion ) age
20-30s
50
Bizarre parosteal osteochondromatosis ( Nora's lesion ) clinical
benign lesion but w/ high local recurrence
51
location for chondro sarcoma
metaphysis
52
age for chondro sarcoma
40
53
clinical chondro sarcoma
primary ( de novo) secondary from osteochondroma enchondroma, etc pain
54
Radiology chondro sarcoma l
lucent metaphyseal lesion with calcifications may have sclerotic margins
55
location for clear cell chondrosarcoma
epiphysis
56
age for clear cell chondrosarcoma
40
57
clinical clear cell chondrosarcoma
resembles chondroblastoma but pt is 40 yo
58
radiology of clear cell chondrosarcoma
dedifferentiated chondrosarcoma | both low grade and high grade tissue present
59
location for non ossifying fibroma
medullary LE arise at growth plate and migrate to diaphysis with pt growth
60
age of non ossifying fibroma
common 40% of children
61
clinical non ossifying fibroma
asymptomatic until fracture; natural hx=regresion; jaffe-campanacci syndrome = multiple NOFs with cafe au lait spots NF1- multile NOFs
62
Radiology of non ossifying fibroma
geographic sclerotic border DO NOT BIOPSY!!!!!
63
location of fibrous dysplasia
usually unilateral
64
clinical fibrous dysplasia
presents w/ deformity sometimes pain secondary to fx albright's syndrome = cafe au lait polyostotic FD, endocrine abnormalities eso precocious puberty Mazabrauds' syndrome = polyostotic FD w/ intramuscular myxomas
65
Radiology of fibrous dysplasia
``` benign firboosseous lesion of bone 25% polyostotoc usually geographic ground glass matruc can have dense areas of calcifications MR: hypointense on T1 hyperintense on T2 but frequently heterogenous enhances with gadolinium BUT may have custic non enhancing areas ```
66
ocation for osteofibrous dysplasia (ossifying fibroma )
intracortical FD almost always tibia
67
age for osteofibrous dysplasia (ossifying fibroma )
early childhood | becomes stable
68
clinical osteofibrous dysplasia (ossifying fibroma )
usually painless | may be related to adamantinoma
69
radiology of osteofibrous dysplasia (ossifying fibroma )
ground glass cortical lesion
70
location for fibrisarcoma & mfh
metaphysis | age for
71
age for fibrisarcoma & mfh
3rd-6th decade
72
clinical for fibrisarcoma & mfh
may arise secondary to other lesions including infarcts
73
radiology for fibrisarcoma & mfh
agressive lytic lesion no matric no periosteal rx

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