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Tumors > Tumors 2 > Flashcards

Tumors 2 Flashcards

1
Q

What % of neuroblastomas metastasize?

A

50%

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2
Q

What % of neuroblastomas calcify?

A

66% (Yochum)

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3
Q

What is the M/C abdominal tumor in a child, according to Yochum? What is the 2nd M/C?

A 
1st = Neuroblastoma
2nd = Wilm's
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4
Q

What is the M/C locations for a solitary plasmacytoma?

A

Mandible, ilium, vertebrae, ribs, proximal femur & scapula

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5
Q

What % of osteosarcoma is radiopaque? What % is mixed? What % is lytic?

A 
Sclerotic = 50%
Mixed = 25%
Lytic = 25%
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6
Q

Which type of periosteal rxn is classic for ostoesarcoma?

A

Sunburst

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7
Q

Osteosarcoma is most likely to mets to where?

A

Lung => cannonball mets

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8
Q

What radiographic sign is present in 30% of parosteal osteosarcoma cases that separates the tumor from the cortex?

A

String sign (or cleavage plane)

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9
Q

Which contrast medium was known to malignantly degenerate into secondary osteosarcoma?

A

Thorotrast

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10
Q

What is the M/C location for an extraosseous osteosarcoma?

A

thigh

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11
Q

True or false: pain is a reliable work up for a suspected chondrosarcoma.

A

False – often just swelling with no pain until it fx or pushes painful structures

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12
Q

What is the M/C primary malignant tumor of the hand?

A

chondrosarcoma

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13
Q

What is the M/C primary malignancy of the pelvis? 2nd? 3rd?

A 
1st = Ewing's
2nd = Osteosarcoma
3rd = Chondrosarcoma
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14
Q

What is the M/C primary malignancy of the chest wall (including sternum & scapula)?

A

Chondrosarcoma

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15
Q

What is the % risk of malignant degeneration of HME?

A

20%

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16
Q

What is the % risk of malignant degeneration of osteochondroma?

A

<1%

17
Q

What is the % risk of malignant degeneration of Ollier’s?

A

10%

18
Q

What is the % risk of malignant degeneration of Maffuci?

A

25%

19
Q

Histology of Ewing’s sarcoma is most similar to which other tumors?

A

Myeloma, non-Hodgkin’s lymphoma, neuroblastoma, leukemia and EG

20
Q

Younger patients who develop Ewing’s are likely to develop it where? And older patients are likely to develop it where in the skeleton?

A 
Younger = peripheral
Older = axial
21
Q

Axial involvement in Ewing’s is likely to affect what region of the spine?

A

Lumbar & sacrum

22
Q

What is an early and characteristic radiographic finding seen with Ewing’s sarcoma?

A

cortical sauceriation

23
Q

What is the M/C location for bone mets from Ewing’s?

A

Spine

Can present with skip lesions => multiple lesions in one bone; also seen in osteosarcoma

24
Q

What % of patients present with a path fx as the initial complaint in fibrosarcoma?

A

33%

25
Q

Bone infarcts malignantly degenerate to which tumor?

A

Fibrosarcoma or malignant fibrous histiocytoma

26
Q

According to Yochum, which tumor is the only primary malignant bone tumor to cross the intervertebral disc and involve adjacent segments?

A

Chordoma

27
Q

Chordoma in which region of the spine is most likely to have calcification?

A

Sacrococcygeal & clivus (VB location rare)

28
Q

Which lymphoma is more likely to be painful (rather than clinically silent)?

A

Hodgkin’s lymphoma (Non-hodgkin’s is usually silent)

29
Q

Which form of lesion is more likely to be painful in Hodgkin’s lymphoma, lytic or blastic?

A

Lytic

30
Q

Where is the M/C location for Hodgkin’s lymphoma to affect?

A

Thoracolumbar region

31
Q

Where is the M/C location for an adamantinoma?

A

Anterior tibia (next M/C is jaw)

32
Q

What are the radiographic features of adamantinoma?

A
  • lytic bone blister cortical appearance
  • sawtooth loss of cortical bone
  • multichambered, bubbly lesion
  • eggshell cortical thickening & spool-shaped bulges of cortex

Tumors (2 decks)

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