Tumormarker Flashcards

1
Q

CK8,18,19

A

Adenokarzinom

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2
Q

PSA/PSP

A

Prostata

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3
Q

Thyreoglobulin

A

Schilddrüse

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4
Q

TTF-1

A

Schilddrüse, Lunge

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5
Q

Hep-Par-1

A

Leber

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6
Q

ER/PgR

A

Mamma

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7
Q

MGMT

A

Glioblastome
Promotor methyliert: gut
Prädiktiv: ansprechen auf alkylierende Chemotherapie
Prognostisch

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8
Q

1p/19q deletion

A

Oligodendrogliome
Bessere Prognose
Prädiktiv für ansprechen auf adjuvante PCV Therapie
Diagnostisch

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9
Q

IDH1/2

A

Isocitratdehydrogenase, Mutation
Nicht Prädiktiv
Diagnostisch für diffuse gliome und sekundäre glioblastome -> prognostisch

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10
Q

CK 5/6,14,16,17

A

Plattenepithelkarzinom

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11
Q

Alpha-fetoprotein (AFP)

A

Hepatozelluläres Karzinom

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12
Q

Karzinoembryonales antigen (CEA)

A

Adenokarzinome GI Trakt, Lunge, Pankreas

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13
Q

CA19-9

A

Adenokarzinom GI Trakt

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14
Q

CA-125

A

Ovarialkarzinom

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15
Q

CDX-2

A

GI-Trakt

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16
Q

Neuroendokrine Marker

A

CD56, NSE= neuronspezifische enolase, synaptophysin

17
Q

MIB-1

A

Proliferationsmarker