Tumormarker Flashcards

1
Q

CEA?

A

Carcinoembryonales Antigen; Kolon, Mamma, BC NSCLC), Magen, Pankreas, medulläres SD, Prostata

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2
Q

AFP?

A

HCC

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3
Q

S100

A

Malignes Melanom, Phäochromozytom, neuroendokrine Tumoren

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4
Q

Pleuramesotheliom

A

Mesothelin, Calretinin, Thrombomodulin, WT-1, Vimentin, D2-40

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5
Q

Plattenepithel-CA der Lunge

A

P40, CK5/6

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6
Q

MDM2, CDK4?

A

Retroperitoneales Liposarkom

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7
Q

NSE?

A

Kleinzelliges Bronchial-CA, neuroendokrine Tumoren, Neuroblastom

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8
Q

CYFRA 21-1

A

BC (NSCLC)

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9
Q

GIST

A

CD117, DOG

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10
Q

TTF1?

A

Lungen-adenokarzinom

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11
Q

Medulläres sD-CA?

A

Calcitonin, Synaptophysin, Chromogranin A

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12
Q

CEA plus CA19-9

A

IPMN, Duktales Adenokarzinom, Pankreas, Kolon-CA

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13
Q

Wann NSE erhöht?

A

Kleinzelliges BC, Neuroendokrine Tumoren, Neuroblastom

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14
Q

CK5/6 (Zytokeratine)

A

Plattenepithel-CA

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15
Q

CD56

A

Großzelliges Bronchial-CA (auch Synaptophysin)

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16
Q

Amsterdam-Kriterien für HNPCC?

A

3-2-1: 3 Erkrankte in 2 Generationen und einer davon unter 50 (wenn nicht alle zutreffen, Bethesda-Kriterien)
Assoziierte Tumoren mit dem Lynch-Syndrom: Endometrium, Ovarial, Magen, Urothel, Dünndarm, Gallengang, CRC