Tumor Virus and Oncogenesis

Question 1

Which of the following mutilfactorial combinations leads to an elevated cancer risk

Answer 1

a) EBV infection and aflatoxin exposure.
b) HBV infection and chromosomal translocations involving the c-myc gene.
c) KSHV infection and immunosuppression.
d) KSHV infection and chromosomal translocations involving the c-myc gene.
e) None of the above

Question 2

Which of the following oncogenic viral proteins blocks Rb1 function?

Answer 2

a) E5
b) E6
c) E7
d) LMP-1
e) Middle T