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Oncogenes > Tumor Suppressor Genes > Flashcards

Tumor Suppressor Genes Flashcards

1
Q

APC

A

Colorectal cancer

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2
Q

BRCA1 (chromosome 17)

BRCA2 (chromosome 13)

A

Breast and ovarian cancer

DNA repair protein

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3
Q

CPD4/SMAD4

A

pancreatic cancer

DPC (“Deleted in Pancreatic Cancer”)

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4
Q

DCC

A

Colon Cancer

DCC (“Deleted in Colon Cancer”)

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5
Q

MEN1

A

MEN type I

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6
Q

NF1 (chromosome 17)

NF2 (chromosome 22)

A

NF1: RAS GTPase activating protein
NF2: Merlin protein (shwannomin)

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7
Q

p16

A

Melanoma

Cyclin-dependent kinase inhibitor 2A

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Oncogenes (3 decks)

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