Tumor Suppressor Genes Flashcards

1
Q

Hereditary neuroblastoma

A

RB

Retinoblastoma, osteosarcoma

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2
Q

Li-Fraumeni syndrome

A

P53

Sarcomas, breast cancer

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3
Q

Familial melanoma

A

P16INK4a

Chondrosarcoma, osteosarcoma, melanoma

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4
Q

Familial adenomatous polyposis

A

APC

Colon adenomas, desmoids

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5
Q

Neurofibromatosis

A

NF1

Neurofibroma, sarcomas

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6
Q

Hereditary multiple exostosis

A

EXT1/EXT2

Osteochondromas, chondrosarcomas

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