Tumor Suppressor Genes Flashcards
1
Q
Hereditary neuroblastoma
A
RB
Retinoblastoma, osteosarcoma
2
Q
Li-Fraumeni syndrome
A
P53
Sarcomas, breast cancer
3
Q
Familial melanoma
A
P16INK4a
Chondrosarcoma, osteosarcoma, melanoma
4
Q
Familial adenomatous polyposis
A
APC
Colon adenomas, desmoids
5
Q
Neurofibromatosis
A
NF1
Neurofibroma, sarcomas
6
Q
Hereditary multiple exostosis
A
EXT1/EXT2
Osteochondromas, chondrosarcomas