Tumor Supp/Oncogenes Flashcards
1
Q
CML, ALL?
A
ABL
- protooncogene/tumor promoter
2
Q
Melanoma?
A
BRAF
PO/TP
3
Q
Squamous cell lung cancer?
A
HER1
PO/TP
4
Q
Breast cancer, ovarian cancer?
A
HER2
PO/TP
5
Q
Neuroblastoma
A
NMYC
PO/TP
6
Q
SCLC?
A
L-myc
PO/TP
7
Q
Burkitts?
A
C-myc
PO/TP
8
Q
Lung cancer, colon cancer, pancreatic cancer?
A
RAS
PO/TP
9
Q
Pancreatic cancer, colon cancer, adenocarcinoma of lung?
A
KRAS
PO/TP
10
Q
Bladder cancer?
A
HRAS
PO/TP
11
Q
Astrocytoma, osteosarcoma ?
A
SIS
PO/TP
12
Q
Astrocytoma, hepatocelluar carcinoma?
A
TGFA
PO/TP
13
Q
Stomach cancer, colon cancer, pancreatic cancer, FAP?
A
APC/B-catenin (Antioncogene, stomach cancer
14
Q
Colon cancer?
A
DCC
Antioncogene/TS
15
Q
RB, osteosarcoma, other cancers?
A
RB
antioncogene
16
Q
most cancers, li-fraumeni
A
TP%3
TS
17
Q
VHL, RCC?
A
VHL
ntioncogene, TS
18
Q
Wilms tumor?
A
WT1
anti-oncogene, tumor suppressor
