Tumor Supp/Oncogenes Flashcards

1
Q

CML, ALL?

A

ABL

- protooncogene/tumor promoter

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2
Q

Melanoma?

A

BRAF

PO/TP

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3
Q

Squamous cell lung cancer?

A

HER1

PO/TP

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4
Q

Breast cancer, ovarian cancer?

A

HER2

PO/TP

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5
Q

Neuroblastoma

A

NMYC

PO/TP

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6
Q

SCLC?

A

L-myc

PO/TP

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7
Q

Burkitts?

A

C-myc

PO/TP

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8
Q

Lung cancer, colon cancer, pancreatic cancer?

A

RAS

PO/TP

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9
Q

Pancreatic cancer, colon cancer, adenocarcinoma of lung?

A

KRAS

PO/TP

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10
Q

Bladder cancer?

A

HRAS

PO/TP

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11
Q

Astrocytoma, osteosarcoma ?

A

SIS

PO/TP

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12
Q

Astrocytoma, hepatocelluar carcinoma?

A

TGFA

PO/TP

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13
Q

Stomach cancer, colon cancer, pancreatic cancer, FAP?

A

APC/B-catenin (Antioncogene, stomach cancer

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14
Q

Colon cancer?

A

DCC

Antioncogene/TS

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15
Q

RB, osteosarcoma, other cancers?

A

RB

antioncogene

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16
Q

most cancers, li-fraumeni

A

TP%3

TS

17
Q

VHL, RCC?

A

VHL

ntioncogene, TS

18
Q

Wilms tumor?

A

WT1

anti-oncogene, tumor suppressor