Tumor Lysis Syndrome Flashcards
Are released to the BS more rapidly than it is eliminated
K and Purines
What is TLS?
Large number of tumor cells are rapidly destroyed
Positive sign that treatment is effective
TLS
Severe TL can cause?
Tissue damage and death
What happens when K levels increase?
Cardiac dysfunction
Large amount of Uric acid
Hyperuricemia
TLS is seen with which type of cancer
Leukemia, lymphoma, small lung cell cancer, myeloma
Dilutes K, increases filtration and excretion of kidneys; best action
Hydration
Help prevent Uric acid precipitation
Alkaline
When n/v occur?
Antiemetic regimen
To promote urine flow but have to be cautious
Diuretics
To lower hyperkalemia
Sodium polystyrene sulfonate
Severe hyperkalemia
Insulin and glucagon IV and dialysis