Tumor HO SKEL B

Question 1

Name two bone tumors that like the epiphysis

Answer 1

Chondroblastoma

Giant cell Tumor/after closure of growth plate

Question 2

6 tumors that prefer the metaphysis

Answer 2

Osteosarcoma
Chondsarcoma
Fibrosarcoma
Non-ossifying fibroma (NOF)
Giant cell tumor/prior to growth plate closure
Unicameral bone cyst (solitary bone cyst) (simple bone cyst) SBC

Question 3

MOCEF preferred time of orgin

Answer 3

M   5,6,7   (age 40 and beyond)
O   2,3       (Under 30)
C   4,5,6   (Over 30)
E   2            (Under 30)
F   4            (Over 30)

Question 4

Most common malignant tumors of the skeleton?

Answer 4

Metastatic bone tumors

Question 5

Big 6 - strongest potential to spread to bone:

Answer 5

Breast
Lung
Prostate
Kidney
Ewing’s
Neuroblastoma 

*males 60% prostate, 25% lung; Females 70% breast

Question 6

The usual metastatic route is via tumor emboli in the vascular system, bones that are rich in red bone marrow are predisposed to develop osseous mets. VENOUS or ARTERIAL side usually?

Answer 6

Venous side

Question 7

Metastasis to BONE is the #______ MC site of metastatic spread.

Answer 7

3rd, after lung and liver

Question 8

What can stimulate osteoBLASTIC cells, producing osteoblastic Mets?

Answer 8

Presence of cancer cells within the bone marrow

Question 9

What could cause inhibition of osteoblastic activity, producing a LYTIC area, osteolytic metastasis?

Answer 9

physical bulk of the tumor

Question 10

What percentage of occurrence for Lytic, blastic and mixed Mets?

Answer 10

Lytic 75%

Blastic 15%

Mixed 10%

Question 11

What percent of all osseous Mets will be found in the axial skeleton?

Answer 11

80%

10% in cranium

10% extremities