Tumor-associated Antigens Flashcards by Marianne Antoinette Bernardino

Q

Multiple myeloma - Affects the lymphoid
tissues

A

Bence Jones Protein

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Q

Nonseminomatous testicular cancer

Choriocarcinoma

Hormone; common in
pregnant women

A

Human Chorionic Gonadotropin

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Q

Familial medullary thyroid carcinoma (Hormone)

A

Calcitonin

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Q

Prostate cancer

A

Prostate-specific antigen (PSA)

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Q

Ovarian adenocarcinoma

A

CA-125

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Q

Sarcomata
Hematopoietic origin

A

Cytokeratins

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Q

Malignant melanoma

A

HMB-45 (Human Melanoma Black)

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Q

Small cancers of the lung
Endocrine tumors

(Pathologic Diagnosis)

A

Neuron-specific enolase

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Q

Neuroendocrine tumors
Melanoma

A

S-100

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Q

Lymphoma (Staging)

A

Beta-2- microglobulin
Lactate dehydrogenase

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Q

Breast adenocarcinoma (Staging)

A

Estrogen receptor

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Q

Hematopoietic malignancies

Bone marrow cell markers assoc. with malignancies

A

CD45

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Q

T cell leukemia

A

IL-2 receptor (CD25)

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Q

Clonality indicates B cell malignancy

A

Monoclonal Ig

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Q

Colonic and pancreatic adenocarcinoma

A

CA-19.9

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Q

Breast adenocarcinoma (Monitoring) -markers
have diff. use

A

CA-15.3

Q

Prostatic adenocarcinoma - used for
localization

A

Prostate-specific membrane antigen (PSMA)

Q

Small cell lung cancer (Localization of metastasis)

A

NRLU-10 (Ab name)

Q

Lymphoma (Localization of metastasis)

A

B-1

Q

Lymphoma (Therapy)

A

CD20

Q

Melanoma (Therapy)

A

MAGE (Melanoma-Associated Antigen)

Q

Breast Carcinoma-associated Ag

A

CA 27.29

Q

Recurring epithelial ovarian cancer

A

Human epididymis protein 4

Q

Urinary bladder cancer

A

Nuclear matrix protein 2
(NMP-22)

Bladder tumor associated Ag (BTA)

Complement factor
H-related protein
(CFHRP)

Q

Lung cancer

A

Cytokeratin fragment
21-1 (CYFRA 21-1)