Tuesdays final drug variables, risk for infection, hypersensitivity, abnormals of immunity Flashcards
Variables that influence drug action
Age, Weight, physical health, psychological aspects, dependence, Sex, environmental temperature, Dosage forms,amount of food in the stomach, cumulative effects.
Risks for infection
Age, malnutrition, invasive, immunocompromised
Hypersensitivity
an abnormal condition characterized by an excessive reaction to a particular stimulus
hypersensitivity disorders involves….
an allergic response and tissue rejection
Immunodeficiency disease…
involves altered and failed immune response
Autoimmune disease involves
extensive tissue damage resulting from an immune system that seemingly reverses its function to one of self destruction.
host response to an allergen
the more sensitive the individual the greater the allergic response is
nature of an allergen
most allergic reactions are precipitated by complex, high molecular weight protein substances
exposure amount
the more allergen the individual is exposed to the greater the chance of severe reaction is
Repeated exposure
generally the more the person is exposed the greater the response is
signs and symptoms of a hypersensitivity may include…
pruritus, nausea, uneasiness, sneezing, excessive nasal secretions, lacrimation, inflamed nasal membranes, skin rash or areas of raised inflammation, diarrhea, cough, wheezes, impaired breathing and hypotension