Tubular resorption/secretion Flashcards
Angiotensin II
increases Na+ and water resorption in PCT, secretion of H+ (stimulation of the antiporter for Na/H); secreted due to renin secretion in response to increased SNS stimulatio
Aldosterone
released from adrenal glands in response to Ang II secretion and hyperkalemia; increases resorption of Na+ and secretion of K+ in principle cells, stimulates secretion of H+ in intercalated cells (ATPase - so also resorbs HCO3-)
ANP
released from atrial cells in response to stretching; directly inhibits Na+ reabsorption in the collecting duct and suppresses secretion of renin and ADH
PTH
released from parathyroid glands in response to hypocalcemia; increases calcium reabsorption in thick ascending LOH (stimulation of Ca/Na antiporter), decreases HPO42- reabsorption in the PCT by decreasing the symporter
Where are the tubules impermeable to water?
late DCT and CD; ascending LOH