Tuberculosis TB

Question 1

3 main regions = 80% of TB worldwide

Answer 1

Asia, C & S Africa, Brazil

Question 2

Immunisation is

recommended in the UK for

Answer 2

• New entrants from endemic areas, if
  unvaccinated and under 16 or under 35
  from area of incidence > 500/100,000
  • Health care workers in at risk areas, if
  unvaccinated and after Mantoux
  • Contacts of active TB cases
  • At risk of TB (workers in prisons,
  homeless hostels, visiting endemic
  countries for > 1 month)
• BCG vaccination for neonate at increased risk
  of TB should be discussed with the parents or
  legal guardian:
  – in areas of UK where annual TB incidence
  >40/100,000
  – with parents/grandparents born in a country where
  annual TB incidence >40/100,000
  – Same for child up to 16, after negative Mantoux
  • Primary care organisations with a high
  incidence of TB should consider vaccinating all
  neonates soon after birth.

Question 3

Immunisation is recommended

in high incidence countries

Answer 3

All neonates (even if possibly HIV positive,
then follow up for signs of disseminated BCG
TB)
• Infants exposed to infectious TB case shortly
after birth, give 6/12 IPT before vaccination
• Protects against leprosy and Buruli ulcer