Tuberculosis Flashcards
Tuberculosis etiology
Mycobacterium tuberculosis
Isoniazid is aka
INH
TB is called “multidrug-resistant tuberculosis” (MDR-TB_ if it is resistant to…
Isoniazid (INH) and rifampin
TB occurs disproportionately to what categories of people?
Poor, underserved, and minorities
People who are at higher risk for TB
Poor, underserved, minorities, IV drug users, people living in over-crowded conditions, poor sanitation, immunosuppressed
What are the three classifications of TB?
Primary, Latent, Reactivated
In primary TB, the patient inhales the bacterium which starts the __ __. s
Inflammatory reaction
In primary TB, most patients mount an effective immune response that…
encapsulates organisms for the rest of their lives
In primary TB, the patient is usually __.
Asymptomatic
Is someone with primary TB contagious?
No
Persistent state of immune response to bacterium with no clinical manifestations of active TB
Latent TB
Is a patient with latent TB contagious?
No
What symptoms do patients with latent TB have?
None
A patient with latent TB with have a __ TB skin test.
Positive
Can a person with latent TB spread it to others?
No
What is the concern with a patient who has latent TB
They can develop active TB at some point
Active TB aka
Reactivated TB
What percent of patients with latent TB develop reactivated TB?
5-10%
How long does it take for a patient with latent TB to manifest symptoms of reactivated TB?
It can take years
The risk of developing reactivated TB is much higher in what groups?
Elderly and immunosuppressed
Is someone with reactivated TB contagious?
Yes
A patient with latent TB may or may not have what on a chest x ray?
ghon nodule
positive TB skin test is a clinical manifestation of __ TB
latent
positive sputum AFB is a clinical manifestation of __ TB
reactivated
Sputum AFB stands for
sputum acid fast bacillus
Point at which a patient with TB is contagious
Positive for AFB
Symptoms a patient with active TB
Fever, night sweats, weight loss, productive cough with purulent or bloody sputum for longer than 3 weeks
How long does a patient with active TB experience a productive cough?
For longer than 3 weeks
Bloody expectorate aka
hemoptysis
Two ways to evaluate TB infection
TB skin test and IGRA blood test