TrueLearn Flashcards
Explain the maneuver:
Mattox
Cattell Brasch
Mattox: left medial-visceral rotation
Cattell Brasch: right colon mobilization
Amino acid associated with T cell stimulation
Arginine
Radiotracer or methylene blue for SLNB in pregnancy
Radiotracer (meth blue is teratogen)
Dysplastic changes of basal layer of skin, parakeratosis, dermal solar elastosis
Actinic keratosis (pre-SCC)
Dx of biliary dyskinesia on CCK HIDA
EF <35% at 20 min
Central line type associated with lowest DVT and line infection
Subclavian
Intestinal hamartoma
Hyperpigmented oral lesions
Breast, cervical, thyroid, lung ca
Peutz Jeghers
Associated tumor marker:
- Embryonal cell ca, ovarian chorioca, mixed germ cell
- Yolk sac, embryonal cell, immature teratoma
- Dysgerminoma
- Granulosa cell
- Embryonal cell ca, ovarian chorioca, mixed germ cell: HCG
- Yolk sac, embryonal cell, immature teratoma: AFP
- Dysgerminoma: LDH
Gastrinoma: M or F predominant?
Male 2:1
Contraindication to nitrous oxide
SBO (air filled cavities)
Acid-base dx after pancreas txp
Met acidosis from HCO3 losses in pancreatic secretions
When in gestation does alveolar phase of development begin
7 months
Phyllodes margin and recurrence rate
1-2 cm margins
20% recurrence
First step in massive hemoptysis
Rigid bronch and packing
ID the liver lesion:
- Homogenous enhancement of hypodense lesion with central scar
- Heterogenous mass with arterial phase enhancement
- Low density and peripheral nodular enhancement
- Homogenous enhancement of hypodense lesion with central scar: FNH
- Heterogenous mass with arterial phase enhancement: adenoma
- Low density and peripheral nodular enhancement: hemangioma
Child’s scores and corresponding surgery mortality
A: 5-6 points -> 10% mortality
B: 7-9 -> 30%
C: 10-15 -> 80%
Preop medical tx of adrenal aldo-secreting tumor
Spironolactone/eplerenone and K+
Tx of Frey Syndrome
Antiperspirant application to affected skin
If refractory -> tympanic neurectomy
Best route for esophageal substitution
Posterior mediastinum
Reason for urinary retention acutely post-hemorrhoidectomy
Pelvic floor muscle spasm
Mechanism by which hypomagnesemia results in hypocalcemia (2)
- Impaired PTH release
- Impaired PTH receptor sensitivity
Immediate tx for ABO incompatible blood transfusion
Stop transfusion
Large volume fluid resusc
Two genes associated with HNPCC
MSH2, MLH1
Workup of bile reflux gastritis after Billroth
EGD and [bile] in gastric secretions OR HIDA
Minimum roux limb length in ReY gastrojejunostomy to avoid bile reflux
45 cm
Types A and B aneurysm size criteria for repair
Type A: >=5.5 cm
Type B: >=6.5 cm
Most common source of zone III trauma bleeding
Sacral venous plexus
Indications for radical neck dissection for parotid tumours
High grade malignant tumours (mucoepidermoid, squamous cell), even if clinically N0
Antidote for ethylene glycol poisoning
Fomepizole
How to manage clinically positive nodes in melanoma
FNA -> equivocal -> excisional bx
Criteria for surgery for intussusception
Necrotic bowel, 2+ recurrences, incomplete reduction
Squeeze mass distal to proximal
Secretin stimulation study: Total volume Enzyme level HCO3 - ZES, malnutrition, chronic pancreatitis, cancer, end-stage pancreatitis
ZES: High volume; normal enzyme, HCO3
Malnutrition: Decreased enzyme; normal volume, HCO3
Chronic panc: Low HCO3; normal enzyme, volume
Cancer: Low volume; normal enzyme, HCO3
End stage pancreatitis: Low volume, enzyme, HCO3
Most common site of traction esophageal diverticuli
Mid esophagus
How to do a Puestow
Open duct anteriorly, extend medially to level of GDA, and laterally past all strictures
Tx of LCIS
Excisional bx -> close observation, tamoxifen, or prophylactic bilat mastectomy
Most common presentation for lap band erosion
port site infection
RFs for gastric polyps (2)
Atrophic gastritis and H. pylori
TIPS one-year shunt re-stenosis rate
50%
Most common cause of dysphagia immediately s/p Nissen
Edema; should resolve in 6-8 weeks
Three stages of skin graft survival in recipient site
Imbibition -> inosculation -> angiogenesis
Best patency after angioplasty (artery)
iliac
Indication for liver txp for hilar cholangioca
N0 and M0 unresectable dx
Rule of 6s for AVFs
blood flow >600 mL/min
diameter >0.6 cm
depth 0.6 cm
Aberrant anatomy to consider when dividing gastrohepatic ligament in Nissen
Replaced left hepatic coming from L gastric
Most common site of SB lymphoma
Ileum
Splenic laceration grading (AAST)
1: subcapsular hematoma <10% of surface area
parenchymal laceration <1 cm depth
2: subcapsular hematoma 10-50% of surface area
intraparenchymal hematoma <5 cm
parenchymal laceration 1-3 cm in depth
3: subcapsular hematoma >50% of surface area
ruptured subcapsular or intraparenchymal hematoma ≥5 cm
parenchymal laceration >3 cm in depth
4: any injury in the presence of a splenic vascular injury* or active bleeding confined within splenic capsule
parenchymal laceration involving segmental or hilar vessels producing >25% devascularisation
5: shattered spleen
any injury in the presence of splenic vascular injury* with active bleeding extending beyond the spleen into the peritoneum
When to resume physical activity after splenic trauma?
Grade + 2 weeks
Most common cause of AVF thrombosis
Intimal hyperplasia of venous anastomosis
Which component of GCS is most sensitive to neurotrauma
Motor
Type of salivary gland tumor with propensity to metastasize along nerves
Adenoid cystic
Agents that increase or decrease LES tone
Increase LES: gastrin, motilin
Decrease: secretin, CCK, estrogen, progesterone, somatostatin
Most prevalent organism in non-aneurysmal aortic infection
Salmonella
Early vs. interval appy
Early: Early return to work Increased complications (SBO, reoperation, wound infection)
Tx of solitary rectal ulcer syndrome
Conservative: high fiber, biofeedback
Mechanism of diverticular bleed
Rupture of vasa recta
Most devastating cause of PONV following sleeve gastrectomy
Portomesenteric venous thrombosis
Longest phase of the cell cycle
G1 (11 h)
Pharmacokinetics vs. pharmacodynamics
PK: What happens to a drug in the body
PD: What the drug does to the body
Orlistat
Anti-obesity agent that inhibits GI lipases and decreases fat absorption
Cancer associated with vinyl chloride
Hepatic angiosa
When to do classic Whipple (+antrectomy) vs. pylorus-preserving Whipple
Classic when D1 involved
Common burn meds ADR: AgNO3 Ag sulfadiazene Mafenide acetate Neomycin/baci/polymyxin B
AgNO3: hyponatremia
Ag sulfadiazene: neutropenia
Mafenide acetate: met acidosis
Neomycin/baci/polymyxin B: nephrotoxic
Zn deficiency signs (3)
Impaired wound healing
FTT
Rash
Selenium deficiency signs (3)
Cardiomyopathy
Hypothyroidism
Neuro changes
Initial step in improving hypotension in pregnant trauma
Roll to the left (uterus rolls off the IVC)
What group of cells stimulates fibroblasts in wound healing
Macrophages
% weight loss after Lap band Sleeve Bypass Switch
Lap band 40-55%
Sleeve 54-70%
Bypass 60%
Switch 70%
First line tx of stage 4 RCC
Sunitinib, panzopanib
Tx for parotid tumours if
- Benign (warthin, pleomorphic)
- Malignant (mucoepidermoid, adenoid cystic)
- Benign (warthin, pleomorphic): WLE
- Malignant (mucoepidermoid, adenoid cystic): total parotidectomy, MRND, XRT
Melanoma subtypes with worst and best prognosis
Worst: nodular
Best: lentigo maligna
Cationic trypsinogen gene mutation
Hereditary pancreatitis (PRSS1)
High risk features of BCC/SCC warranting Mohs
Poorly differentiated Face, genitalia, hands/feet >=6mm Depth >=4 mm PN invasion Immunosuppression Marjolin ulcer
First step if gastric conduit does not reach esophagus
Kocher
Signs of contrast nephropathy
Normal UOP SCr >25% elevated Muddy brown casts FeNa <1 Mild proteinuria
Most common gene mutation in pancreatic cancer
K-ras
Most common complication of I and D
bleeding
Diagnosis of melanoma (what kind of bx)
Must be full thickness bx
Margins for melanoma WLE
is: 0.5-1 cm
<1 mm: 1 cm
1-2 mm: 1-2 cm
>2 mm: >=2 cm
Where should you not place tacks in IHR
Inferior to iliopubic tract and lateral to epigastrics (neurovascular injury)
Best tx for low grade gastric MALT
Abx for hP
Tx for gastric band slippage
Concern for ischemia so immediately remove saline from band and go to OR for band removal
Only effective chemo for HCC
Sorafenib (VEGF inhibitor)
Milan criteria for resectable HCC (3)
<5 cm lesion
<=3 lesions each smaller than 3 cm
No extrahepatic dx
Tx of asymptomatic histoplasmosis
Nothing
Bx margin for suspected melanoma
Full thickness bx with 1-2 mm margins
Goal lactate in resuscitation of trauma
<2.5
Which organism that causes PID is most associated with infertility
Chlamydia
Size at which adrenal masses should be resected
> 6 cm
Tx for supracondylar humerus fx
Closed reduction with pin fixation
Most common organism in lymphangitis
Group A strep
For ITP splenectomy, when is plt transfusion given
Right after splenic artery ligation
% ICA stenosis at which to perform CEA
Sx: >50%
Asx: >60%
Calcitonin effect on PO4
Promotes PO4 excretion
HCG criterion for MTX for ectopic pregnancy
HCG <=5000
Hepatoblastoma associated with which familial syndromes
Beckwith-Wiedmann Hemihypertrophy Li Fraumeni FAP T18
% of total daily calories to be given as N2 in patients with malnutrition needing TPN
15%
Most anterior and posterior structures in porta hepatis
Anterior: artery
Posterior: portal vein
Tx for choledochal cysts type: 1 2 3 4
1/4: hepaticojej
2: Cyst excision, primary closure of CBD
3: ERCP marsupialization or transduodenal excision
Type of mesh to use in splenorrhaphy for trauma
Absorbable
Tx for recurrent anal canal SCC
APR
Respiratory quotient
CO2 produced/O2 consumed
Best operation for Crohn duodenal strictures causing obstructive sx
Gastrojejunostomy
Manometry findings for scleroderma esophageal dysmotility (amplitude, type of contractions, LES pressure)
Low amplitude
Simultaneous contractions
Normal/low LES pressure
Anterior to posterior thoracic outlet: scalene, axillary nerve, axillary vein, brachial plexus
Vein
Muscle
Artery
Nerve
Tx of radial scar (breast)
Excisional bx
PE finding for obturator hernia
Medial thigh pain elicited by internal rotation and extension of thigh (Howship-Romberg sign)
What is the organ with the highest K secretion?
Colon
Dermatofibrosarcoma protuberans
- Signs
- Path
- Tx
Firm, red plaques that resemble keloids
Path: finger-like projection of spindle cells
Tx: WLE w/ 2 cm margins or Mohs; adjuvant XRT if >5 cm
First step in evaluating bloody diarrhea s/p AAA repair
Sigmoidoscopy
Latent error
System defect that is insidious until a mistake is made
Tx of nitroprusside toxicity
Amyl nitrite
Criteria for transanal resection of rectal cancer:
- Size
- Location (cm from verge)
- T grade
- High risk features
- % circumference involved
- Size < 3cm
- Location (cm from verge) <8 cm
- T1
- High risk features: no mucin, no LV involvement
- % circumference involved: <30%
CN XI
- Where does it exit
- Which nerve roots
- Muscles supplied
- Exits in jugular foramen
- C1-5
- SCM, trapezius
Cell origin of GIST
Interstitial cells of Cajal
McVay repair
Approximate transversus abdominus to Cooper’s ligament with relaxing incision on anterior rectus
Good for emergent femoral hernia repair
Between which two abdominal muscle layers is mesh placed in Rives-Stoppa VHR
Between rectus muscle and posterior rectus sheath
Tx of unresectable hepatoblastoma
Neoadjuvant cisplatin -> try to make it resectable
Tx of multiloculated splenic abscess
Splenectomy
4 types of cholangiocarcinoma
1: common hepatic duct only
2: hepatic bifurcation
3: secondary hepatic ducts on one side
4: secondary hepatic ducts on both sides
Size of Zenker above which diverticulectomy is added to myotomy
> 2 cm
Goal UOP in electrical burns
2 ml/kg/hr
Signs of cholestasis/bile leak after liver txp associated with what vascular condition?
Hepatic artery thrombus
Most common presenting symptom for pseudomyxoma peritonei
Widening abdominal girth
Tx for CIN 1 vs. CIN2-3
CIN1: Observation
CIN2-3: LEEP
Tx for simple intersphincteric fistula
What if sphincter involved?
Intersphincteric: fistulotomy
If significant sphincter involvement: seton
EKG findings in PE
S1Q3T3
Anterior leads T wave inversion
What does NOT improve after colectomy for UC (2)
PSC
Ankylosing spondylitis
Initial workup of suspected gastroparesis
EGD -> gastric emptying study
Most common postop complication after kidney txp
PGD
Safest laparoscopic access in redo abdomen
Hasson
Hypothermia: Temp, sx?
- Mild
- Mod
- Severe
Mild: 32-34 C; shivering, AMS, tachycardia
Mod: 29-32 C; agitation, spasticity, afib, hypotension
Severe: 21-29 C; prolonged QRS, osborn waves, flaccid, coma, vfib, death
Profound: <21C; death
Energy in kcal/g for TPN Lipid Protein Oral carbs Dextrose
Lipid 9
Protein 4
Oral carbs 4
Dextrose 3.4
Risk factors for small bowel adenocarcinoma (4)
Crohns
FAP
HNPCC
Celiac
Tx for gastric cardia >T2N0 cancer
Number of nodes?
Neoadjuvant chemo
TOTAL gastrectomy (to get 5 cm margins)
15 nodes at least
Parastomal hernia
- Best repair
- What if other stoma-related problems?
- Lap repair w/ bio mesh
- If other problems, can just resite stoma and reinforce with bio mesh
Best test to assess for colovesical fistula
CT (air in bladder)
Criteria for neoadjuvant chemo for bladder cancer (2)
T3 or higher (extends into fat)
N+
Tx for positive SLNB in melanoma
Can do completion LNB OR observe (U/S q3-12 mos x 2-3 years)
Tx of F XI deficiency
FFP, NOT purified factor (thrombogenic)
Safest inhalation anesthetic for low EF
Nitrous oxide
Most common organism in early vs. late vascular graft infections
early: s. aureus
late: s. epidermidis
Most potent stimulator of pancreatic enzymes vs. fluid/HCO3
Enzymes: cck
Fluid/HCO3: secretin
Most common malignant peds lung tumors
Pleuropulmonary blastoma #1
Carcinoid
Time interval for operating on thrombosed hemorrhoids
Within 4 days of sx
Minimum diameter of vessel to use bipolar cautery
> =7mm
Tx for retrorectal masses
Always excise
Tx of echinococcus splenic cysts
Sterilize -> splenectomy
Size and chronicity criteria for conservative management of pancreatic pseudocysts
<6 cm and <6 weeks should be conservative management
Enlarging cysts and sx -> cystgastrostomy
Most common malignant tumor of appendix
Adenoca (carcinoids not always malignant…)
Two most common organisms in pyogenic liver abscess
Klebsiella, e. coli
Pancreatic cancer that is associated with ovarian stroma
Mucinous cystic
Where in posterior pituitary is ADH released
Supraoptic and paraventricular nuclei
Four RFs for gb cancer
Cholelithiasis
Choledochal cysts
Porcelain
Polyps
Management algorithm for suspected perineal Paget
First CT abdomen and colonoscopy (50% occult cancer)
Then WLE w/ perianal bx
Most important predictor of survival for pancreatic cancer
T stage (also N stage)
Liver mass w/ central scar but normal AFP and high neurotensin
Fibrolamellar HCC
Most common and most favourable cholangioca type
Most common: Nodular
Most favourable: Papillary
CAH (21 hydroxylase def)
- Na, K
- Which steroid is high
- Low Na, high K
- 17 hydroxyprogesterone high
Most radiosensitive tumour
Seminoma
Tx for Merkel cell carcinoma
WLE, SLNB, adjuvant XRT
Type of EGD (rigid or flexible) for foreign body in esophagus
Flexible is good enough these days (need anesthesia for rigid)
Four poor prognostic factors for neuroblastoma
Age >1
High NSE (neuron specific enolase)
High LDH
N-myc amplification
Minimum artery and vein diameter for AVF creation
Artery > 2mm
Vein > 3mm
Succinylcholine
- How is it eliminated
- Three contraindications to use
- Pseudocholinesterase elimination
- Contraindications: Large burns, spinal cord injuries, renal failure
Which nondepolarizing muscle blocker is safe for anesthesia in renal and hepatic failure
Cistracurium (Hoffman degradation)
Dose of long and short acting insulin the day of surgery
Half of long acting and no short acting
Tx of superficial vs deep septic thrombophlebitis
Superficial: abx, vein excision
Deep: abx, heparin
Tx for ruptured umbilical hernia associated with ascites
Urgent surgery
21 vs. 11 hydroxylase deficiency:
Mineralocorticoid level
K
Na
In 11 hydroxylase def, MC level HIGH, K LOW, Na HIGH
In 21, MC level LOW, K HIGH, Na LOW
Sx of Anterior cord Central cord Posterior cord Brown Sequard Cauda equina
Anterior cord: no motor/pain/temp below level of injury; preserved proprioception, fine touch
Central cord: upper extremity weakness > lower; sacral sensory sparing
Posterior cord: loss of proprioception and vibration only
Brown Sequard: ipsilateral loss of motor, contralateral loss of pain/temp
Cauda equina: areflexive bowel/bladder
Most common site of minor salivary gland tumors
Palate
Bilateral parotid masses associated with smoking
Warthin tumors
Three strongest predictors of operative mortality after CABG
Redo CABG
Prior heart surgery
Low EF
Most common cancer of upper vs. lower lip
Upper: basal cell
Lower: scc
Richter hernia
Contains antimesenteric side of bowel (high strangulation risk)
Most potent stimulator of bile secretion
Secretin
Algorithm of axillary adenocarcinoma with no known primary
Mammo/MRI -> whole body PET -> axillary dissection, chemo/endocrine, whole breast XRT
Depth criterion for SLNB in melanoma
> =0.75 mm (stage IB)
Estimate free H2O deficit
Weight x 0.6 x (Na-140/140)
Steroid of choice in acute adrenal insufficiency
IV dexamethasone
Margins for low risk basal cell carcinoma
0.3-0.5 cm
Most common cause of death in lung txp <1 year and >1 year
<1 year: infection
>1 year: chronic rejection
Most common cause of rectovaginal fistula
Obstetric trauma
Immunosuppressive med and ADRs:
- Tacrolimus
- Sirolimus
- Thymoglobulin
- Mycophenolate
- Cyclosporine
- Tacrolimus: HTN
- Sirolimus: poor wound healing
- Thymoglobulin: fever, hypotension
- Mycophenolate: diarrhea
- Cyclosporine: gingival hyperplasia, hirsutism
Lipoprotein with highest concentration of cholesterol
LDL
Tx of bone spindle cell tumor (malignant fibrous histiocytoma)
Neoadj chemo -> WLE
MCC of portal venous thrombus in kids
Umbilical vein infection
F/U for nonfunctioning small adrenal masses
Imaging at 6, 12, 24 months
Annual hormone testing for four years
Management of indeterminate pathology after FNA of thyroid nodule
Repeat FNA
Most commonly injured nerve in lap IHR
Genitofemoral
Nodular lymphoid hyperplasia in SB and colon associated with what kind of diseases?
Immunosuppression
What is the function of protein C?
It deactivates fVa and fVIIIa by proteolysis
Tx for type II choledochal cyst
Cystectomy and primary CBD closure
Tx for trauma medial or lateral to the lateral canthus of the eye
Medial: can observe
Lateral: must operate
FMD of the carotid
Imaging finding? Tx?
Imaging: beaded stenoses of carotid
Tx: PTCA
INR vs. PTT: which represents extrinsic vs. intrinsic pathway?
INR: extrinsic
PTT: intrinsic (does NOT measure F VII)
Max volume of air that can be expired after max inhalation
Vital capacity
In trauma laparotomy, order in which to pack: inframesocolic, supramesocolic, lesser sac, retroperitoneum
Inframesocolic -> supramesocolic -> RP -> lesser sac
Highest sensitivity initial test for pheo
Plasma free metanephrines
Decreased total exocrine secretion volume in pancreas
Pancreatic cancer
Decreased HCO3 secretion in pancreas
Chronic pancreatitis
Decreased pancreatic enzyme secretion
Malnutrition
Decreased volume, enzyme, and HCO3 from pancreas
End stage pancreatitis ‘burnout’
Tx for cT1 vs. cT2 bladder cancer
T1: TURB + HCG
T2 (muscle invasive)+: Cystectomy, ileal conduit
Worrisome vs. high risk features for IPMN
Worrisome (EUS at least):
Main duct 5-9 mm, change in duct caliber, adenopathy, pancreatitis, BD IPMN > 3 cm, mural nodules, thickened, enhancing wall
High risk (resect):
Main duct >1cm, enhancing solid component within cyst, jaundice
What cancer is CDH1 mutation associated with
Diffuse signet ring cell gastric cancer
Seven variables in Gail’s model
Age
Age at menarche
Age at first child
Family history of breast cancer (first degree)
No. of past breast bx
No. of past breast bx showing atypical hyperplasia
Race/ethnicity
Which enzyme is cleared fastest in pancreatitis?
Amylase
Which pancreatic enzyme is secreted into the duct in its active form?
Lipase
Tx for low rectovaginal fistula
Endorectal advancement flap
Most common location for small bowel lymphoma
Ileum
Electrolyte abnormality associated with Sheehan syndrome
Hyponatremia
Teduglutide
GLP-2 agonist used in short bowel syndrome
Does right or left vagus become posterior? Which gives rise to hepatic branch? Grassi?
Right is posterior. Right: Grassi. Left: Hepatic
In Heller length of myotomy on esophagus and stomach
5-6 cm on esophagus; 2 cm on stomach
Two electrolyte imbalances associated with amphotericin B
Hypokalemia
Hypomagnesemia
Hypertriglyceridemia + hypercholesterolemia are a toxicity of this immunosuppressive medication
Sirolimus
How to calculate expected weight loss after bari surgery
(Current weight - ideal weight)*percent weight loss expected
Most common ectopic location of superior vs. inferior parathyroid gland
Superior: TE groove
Inferior: thyrothymic ligament
- First major steps in liver resection
2. From anterior to posterior, structures in porta hepatis
- Division of ligaments -> chole
2. artery, portal vein, hepatic vein
Type of liver cells present in FNH
Kupffer cells
Signs of essential FA deficiency
Scaly rash
Poor healing
Sparse hair growth
Minimum liver remnant after resection (%)
20%
Most common cause of splenic injury during laparoscopy
Forceful retraction of omentum
Most common and favorable morphology of cholangio
Common: sclerosing
Favorable: papillary
Initial and hourly chest tube output warranting thoracotomy following trauma
> 1.5 L upfront
>200-300 mL/hr