trigeminal Flashcards
the ascending branch of the trigeminal n. ends in _____, which functions primarily for _____
primary sensory nucleus (main/chief/pontine); light touch perception
the descending branch of the trigeminal n. ends in the ____ which has 3 subdivisions:
ends in spinal trigeminal nucleus
3 divisions: nucleus oralis (light touch perception)
nucleus interpolaris (temperature)
nucleus caudalis (pain)
there are two types of ____ mechanoreceptors and two types of ____ mechanoreceptors
rapidly adapting; slowly adapting
____ for mechanoreception is the deformation or stretch of the axon membrane that opens ____ channels, thereby depolarizing the axon and causing impulses
transduction; sodium
type of sodium channel involved in mechanoreception
epithelial NaCl channels
mechanoreception may also occur thru specific ______ channels, an example of which are piezo 1 and piezo 2
transient receptor potential (TRP)
in the ____, there is a correlation between receptor structure and function
hand
response properties of mechanoreceptors are influenced by:
- degree of myelination
- location of the receptor (superficial/deep)
- structure of the ending (degree of encapsulation)(Meissner/Ruffini)
- transduction
pacinian corpuscles are designed to detect ____ stimuli
vibratory
2 types of superficial endings
meissner’s corpuscles and merkel disc
2 types of deep endings
pacinian corpuscle and ruffini ending
4 types of endings and their types
meissner corpuscle (RAI) pacinian corpuscle (RAII) merkel disc (SAI) ruffini ending (SAII)
4 types of endings and what they detect
meissner corpuscle- light touch/spatial discrimination
pacinian corpuscle- vibration
merkel disc- pressure
ruffini ending- skin stretch
lamellae of pacinian corpuscles are composed of ____ and ____ separated by ___ to provide a cushion to applied stimulus
cells; collagen fibers; fluid
upon release of stimulus, ____ of pacinian corpuscle imparts a ____ response to nerve ending
decompression; 2nd (off)
mechanisms of mechanotransduction
- ENaC (epithelial Na channels)
- TRP channels
- Piezo1 and Piezo2
____ are used to measure two-point discrimination (tactile sensitivity)
disks
____ are monofilaments calibrated to bend at specific forces, usually measured in grams
von frey hairs (semmes-weinstein monofilaments)