Trichomonas Vaginalis Flashcards

1
Q

Trichomonas reproduces by……, its definitive host is……

A

Longitudinal binary fission
Human

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2
Q

What are the infective, pathogenic & diagnostic stages of Trichomonas

A

Trophozoite stage

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3
Q

What is the habitat of trichomonas?

A

In female: vagina, cervix, urethra, UB, Bartholin & Skene glands
In male: ant urethra, prostate, seminal vesicles

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4
Q

Describe mode of infection & infective stage of Trichomas?

A
  1. Sexual intercourse is the 1ry mode of transmission of trophozoite (infective stage)
  2. Occasionally, transmitted by toilet seats & fomites
  3. Rarely, mother to infant through birth canal
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5
Q

Describe pathogenesis of trichomoas

A

An obligate noninvasive parasite, causes contact dependent cytopatyic effect of target cells due to toxic & mechanical irritation, it produces proteases & a cell detaching factor that causes detachment of vaginal epithelial cells.

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6
Q

List Predisposing factors to Trichomonas

A
  1. Inc vaginal pH
  2. Superadded infection as gonorrhea
  3. Dec in IgA
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7
Q

Trichomonas vaginalis requires pH……

A

5.0-5.5

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8
Q

Mention factors that interfere with lactic acid production thus predispose to trichomonas

A

a. Dec in number of doderlein bacilli due to OCP,steroids, Abx
b. Hormonal disturbance

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9
Q

IP of trichomoas is….

A

5-28 days

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10
Q

Compare signs of trichomonas in males & females

A

M: white urethral discharge, enlarged tender prostate due to prostatitis
F: leucorrhea (creamy or yellow vaginal purulent frothy discharge with foul odour), strawberry vagina (hyperemia & petechial Hge)

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11
Q

List complications of Trichomonas

A
  1. Pregnant women may a..deliver prematurely, b..have low birth weight baby, c..transmit infection to baby
  2. Postoperative infections
  3. Cervical neoplasia
  4. Trichomonas vaginalis inc risk of HIV transmission
  5. In male, urethral stricture & infertility
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12
Q

Compare diagnostic specimen for Trichomonas in males & females

A

M: urine sediment, semen or prostatic secretion
F: vaginal swab or urine sediment

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13
Q

Fixed smears for Trichomonas are stained by….

A

Giemsa or Papanicolaou stain

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14
Q

Mention media for trichomonas

A

Modified Diamond’s medium or Trussel’s & Johnson’s medium

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15
Q

Drug of choice for Trichomonas is……., in pregnant women it is……

A

Oral metronidazole (Flagyl)
Suppository of Clotrimazole

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