Triads

Question 1

Hyperthyroid with gland enlargement

Infiltrative opthalmopathy

Pretibial myxedema

Answer 1

Graves disease

Question 2

Polyphagia

Polyuria

Polydipsia

Answer 2

Type 1 DM

Question 3

Hyperglycemia

Ketonemia

Metabolic acidosis

Answer 3

DKA

Question 4

Islet cell tumor

Gastric acid hypersecretion

Peptic ulceration

Answer 4

Gastrinoma

Question 5

Diabetes

Cholelithiasis

Steatorrhea

Answer 5

Somatostatinoma

Question 6

Headache

Palpitations

Diaphoresis

Answer 6

Pheochromocytoma

Question 7

Diabetes

Dermatitis

Depression

DVTs

Answer 7

Glucagonoma

Question 8

Watery diarrhea

Hypokalemia

Achlorhydria

Answer 8

VIPoma

Question 9

Pituitary adenoma

Pancreatic endocrine tumors

Parathyroid adenoma

Answer 9

MEN type 1

[can also present with duodenal gastrinoma]; germline mutation in MEN1 tumor suppressor gene (menin)

Question 10

Parathyroid adenoma

Pheochromocytoma

Medullary thyroid carcinoma

Answer 10

MEN 2A

Question 11

Pheochromocytoma

Medullary thyroid carcinoma

Mucosal neuromas

Marfanoid body habitus

Answer 11

MEN 2B

Question 12

Adrenalitis
Parathyroiditis
Hypogonadism
Pernicious anemia
Mucocutaneous candidiasis
Ectodermal dystrophy

Answer 12

Autoimmune Polyendocrine Syndrome Type 1

[mutations in AIRE gene; common cause of primary hypoadrenalism in western world]

Question 13

Adrenalitis
Thyroiditis
Type 1 DM

Answer 13

Autoimmune Polyendocrine Syndrome Type 2