Trematodes (Clonorchis sinensis) (Opistorchis felineus) (Opistorchis verrini)

Question 1

Common name of Clonorchis sinensis

Answer 1

Chinese liver fluke, Oriental liver fluke

Question 2

Clonorchis feed on _____ ______

Answer 2

Tissue fluids

Question 3

Infective stage of Clonorchis sinensis

Answer 3

Metacercaria encysted in the muslces or flesh or under the scaled of the second intermediate host (fish)

Question 4

Habitat of Clonorchis sinensis

Answer 4

Distal capillaries of the bile ducts, pangreatic ducts, and gall bladder.

Question 5

1st intermediate hosts of Clonorchis sinensis (Snails: BSTAMP)

Answer 5

Bumilis striatulus
Semisulcospira sp.
Thiara sp.
Abcinna sp.
Melanoides sp.
Parafossarulus sp.

Question 6

2nd intermediate hosts of Clonorchis sinensis

Answer 6

Freshwater Fish: TCC
Tuna
Cyprinidae sp.
Ctenopharyngodon sp.

Question 7

Diagnostic stage of Clonorchis sinensis

Answer 7

Mature eggs in stool

Question 8

Pathology of Acute stage in Clonorchis sinensis

Answer 8

Hyperplasia
Phases:
a. Desquammation of epithelial cells (DEC)
b. hyperplasia + DEC
c. hyperplasia + DEC + adenomatus tissue formation
d. marked proliferation (leads to fibrosis of bile duct walls)

Question 9

Pathology of Chronic stage in Clonorchis sinensis

Answer 9

Severe liver cirrhosis. Portal hypertension. Usually asymptomatic.

Question 10

Carcinoma of the liver caused by Clonorchis sinensis

Answer 10

Cholangio carcinoma

Question 11

Portal of entry of Clonorchis sinensis

Answer 11

Mouth

Question 12

Symptoms (7)

Answer 12

Fatigue, weakness, weight loss, abdominal distress, fever, hepatomegaly and tenderness, and marked EO

Question 13

Diagnosis

Answer 13

Sedimentation technique, Beale’s String Test - entertube test, ELISA, EIA, and PCR

Question 14

Treatment for Clonorchis sinensis

Answer 14

25 mg/kg Praziquantel

Question 15

Uterus of Clonorchis sinensis

Answer 15

Neatly coiled

Question 16

Ovary of Clonorchis sinensis

Answer 16

Lobed

Question 17

Tegument of Clonorchis sinensis

Answer 17

aspinous (smooth and shiney, no spines/ tuberculation)

Question 18

Oral sucker is __ than ventral sucker in Clonorchis sinensis

>, =, <

Answer 18

>

Question 19

Intestinal ceca of Clonorchis sinensis

Answer 19

Simple and unbranched

Question 20

Testis of Clonorchis sinensis

Answer 20

2 One up, One down. Deeply lobed or dendritic

Question 21

Egg of Clonorchis sinensis

Answer 21

One of the smallest, old-fashioned electric light bulb; pitcher shaped, small knob-like protrusion at posterior portion. Mature with miracidium inside.

Question 22

Route of entry of Clonorchis sinensis

Answer 22

Oral

Question 23

Common name of Opistorchis felineus

Answer 23

Cat liver fluke

Question 24

True of False: Final host of Opistorchis felineus is Cat

Answer 24

False. FH of Opistorchis felineus is Man.

Question 25

1st intermediate host of Opistorchis felineus

Answer 25

Snail: Bumilus tentaculata

Question 26

2nd intermediate host of Opistorchis felineus

Answer 26

Tinca tinca, Barbus barbus, Cyprinidae sp., Ctenopharngodon sp., Tuna (Sushi, sashimi)

Question 27

True or False: Opistorchis verrini is similar with Clonorchis sinensis

Answer 27

True