TREMATODES Flashcards

1
Q

Enumerate the 2 Classes of Trematodes

A

Monoecious Flukes
Dioecious Flukes

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2
Q

Mr. Park, a 62-year-old Korean man, was seen for fatigue,
fever, and abdominal pain. On questioning the patient, it was learned that Mr. Park is a commercial fisherman. His
liver function test results were abnormal, showing elevated
aspartate aminotransferase (350 IU/liter), alanine aminotransferase (352 IU/liter), alkaline phosphatase (204 IU/
liter), and conjugated bilirubin (3.9 mg per deciliter) levels;
total bilirubin was 6.4 mg/dL. His white blood cell (WBC) count was 13,000/mm3 and eosinophilia value was 26%. A computed tomography (CT) scan of the abdomen showed dilation of the common bile duct. A tube was inserted into
the common bile duct and numerous leaf-shaped worms

  1. What parasite(s) do you suspect? Why?
  2. What is the name of the disease/condition associated with this parasite?
A
  1. Clonorchis sinensis. The other trematodes
    that cause infections from eating raw fish,
    metagonimiasis and heterophyiasis, live in the intestine, not the liver.
  2. Clonorchiasis
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3
Q

What is the Intermediate Host for Trematodes?

A

Snail

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4
Q

Enumerate the following

  1. Intermediate Host
    a. Monoecious
    b. Dioecious
  2. Infective Stage
    a. Monoecious
    b. Dioecious
  3. Ova
    a. Monoecious
    b. Dioecious
  4. Cercaria
    a. Monoecious
    b. Dioecious
  5. Adult
    a. Monoecious
    b. Dioecious
  6. Habitat
  7. Adult
    a. Monoecious
    b. Dioecious
A
  1. IH
    a (2 IH: Snails and Fresh water vegetations)
    b (1 IH: Snails)
  2. Infective Stage
    a. Metacercariae
    b. Cercariae
  3. Ova
    a. Operculated
    b. Non-operculated with spines
  4. Cercaria
    a. Straight
    b. Forked/ Bifurcated
  5. Adult
    a. Flat, Leaf-like
    b. Cylindrical, separate sexes
  6. Habitat
    a. Lungs, liver, intestines
    b. Blood vessels
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5
Q

Enumerate
a. Liver flukes
b. Intestinal flukes
c. Lung fluke
d. Blood flukes

A

a. F. hepatica, F. gigantica, C. sinensis, O. felineus, D. dendriticum

b. F. buski, E. ilocanum, H. heterophyes, M. yokogawai

c. P. westermani

d. S. japonicum, S. mansoni, S. knowlesi, S. haematobium

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6
Q

Termed as a lidlike structure for appropriate conditions. Give an example

A

Coperculum
Fasciolopsis & Fasciola

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7
Q

Termed as an organ-dwelling fluke

A

Monoecious

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8
Q

Termed as blood-dwelling flukes

A

Dioecious

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9
Q

Which are TRUE about Trematodes

I. Known as broad flukes
II. Appears to have a leaf-like structure as bilaterally symmetrical
III. Contains a protandry reproductive system

a. I, II
b. II, III
c. I, III
d. All of these

A

D

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10
Q

What fluke is the most important digenetic parasites of man inhabiting the veins of their Host?

A

Dioecious flukes

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11
Q

The first intermediate host for all the trematodes is which of the following?
A. Fish
B. Snail
C. Shrimp
D. Water plant

A

B

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12
Q

Adult trematodes are readily recoverable in clinical samples
A. True
B. False

A

B

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13
Q

Individuals suffering from trematode infections experience a variety of species-dependent symptoms.
A. True
B. False

A

A

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14
Q

Trematodes belong to what Phylum?

A

Platyhelminthes

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15
Q

All are TRUE for Dioecious flukes are, except
I. Dioecious flukes usually lives in pairs
II. Male is grayish in color with gynecophoral canal
III. Females are thread-like/ cylindrical shaped
IV. Infective Stage: Metacercaria
V. Mode of transmission: Skin penetration of snail to humans

a. One of these
b. Two of these
c. Three of these
d. All of these
e. None of these

A

A. Infective stage should be Cercaria

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16
Q

Enumerate the Laboratory Diagnosis for Schistosoma species

a. S. japonicum
b. S. mansoni
c. S. haematobium

A

a. rectal biopsy
b. rectal biopsy
c. bladder biopsy

17
Q

It has the principle based on patient serum precipitation with lyophilized eggs identified under microscope

A

Circumoval Precipitin Test

18
Q

A gold standard for diagnosis for Schistosomiasis

A

COPT (Circumoval Precipitin Test)

19
Q

COPT (Circumoval Precipitin Test)
a. How many drops of suspension is added containing larvae, eggs, or immature
adults
b. How many drops is added for serum
c. Incubate at what temp for how many hours?
d. Describe the (+) Apperance

A

a. 1 drop 0.025 ml
b. 3 drops 0.075 ml
c. 34C for 24 hours
d. Precipitates/ Bleb formation

20
Q

Treatment used for Schistosomiasis

A

✓ Praziquantel
✓ Oxamniquine
✓ Metrifonate
✓ Niridazole

21
Q

What Schistosomes are being described?

  1. Has the common name of Mekong schistosome that is similar with S. japonicum
  2. A common parasite of cattle, sheep, goats and equins
A
  1. S. mekongi
  2. S. bovis
22
Q
A