TREMATODES Flashcards
TREMATODES IS ALSO KNOWN AS
FLUKES
WHAT IS THE SHAPE OF TREMATODES?
LEAF-LIKE (ADULT)
TREMATODES IS A _________ / __________, WHICH MEANS IT HAS A MALEA ND FEMALE REPRODUCTIVE ORGANS
MONOECIOUS / HERMAPHRODITIC
THE INFECTIVE STAGE OF TREMATODES
METACERCARIA
THE LAST LARVAL STAGE OF TREMATODES
METACERCARIA
ATTACH THEMSELVES TO THE HOST BY MEANS OF 2 SUCKERS
TREMATODES
TREMATODES ATTACH THEMSELVES TO THE HOST BE MEANS OF _______
2 SUCKERS
PARTS OF TREMATODE SUCKERS
- ORAL SUCKER
- VENTRAL SUCKER / ACETABULUM
3RD SUCKER SEEN IN HETEROPHYES HETEROPHYES
GENITAL SUCKER / GONOTYL
THE 3RD SUCKER (GENITAL SUCKER / GONOTYL) IS SEEN IN
HETEROPHYES HETEROPHYES
TREMATODES:
1ST INTERMEDIATE HOST
SNAILS
TREMATODES:
2ND INTERMEDIATE HOST
FISH, CRABS, VEGETATION, SNAIL
TREMATODES:
MODE OF TRANSMISSION
INGESTION of 2nd intermediate host infected w/
metacercaria
TREMATODES:
Has operculum, lid-like structure allowing the exit of
larva when they hatch
EGGS
Eggs w/ operculum are called
OPERCULATED OVA
TREMATODES:
LARVAL STAGES
- MIRACIDIUM
- SPOROCYST
- REDIA
- CERCARIA
- METACERCARIA
Tips (Mnemonic): My Sister Rent a Car for Me
ADULT OVA
Oviparous or oviviparous
Trematodes resides in multiple areas of the body:
Liver
Intestine
Pancreas
Lungs
GIVE THE LIVER FLUKES
- FASCIOLA HEPATICA
- FASCIOLA GIGANTICA
- CLONORCHIS IMMITIS
- OPISTHORCHIS FELINEUS
- DICROCOELIUM LANCEOLATA
GIVE THE LIVER FASCIOLIDS
- FASCIOLA HEPATICA
- FISCIOLA GIGANTICA
FASCIOLA HEPATICA IS ALSO KNOWN AS
SHEEP LIVER FLUKE
TEMPERATE LIVER FLUKE
FASCIOLA GIGANTICA IS ALSO KNOWN AS
GIANT LVIER FLUKE
TROPICAL LIVER FLUKE
THE LARGEST LIVER FLUKE
FASCIOLA GIGANTICA
are termed to be Fasciolids
Fasciola hepatica & Fasciola gigantica
NATURAL / FINAL HOST OF Fasciola hepatica
SHEEP
NATURAL / FINAL HOST OF FASCIOLA GIGANTICA
- LOCAL CATTLE
- HERBIVORES
serves as an accidental host for Fasciola hepatica & Fasciola gigantica
man
(when man accidentally ingest a 2nd intermediate host infected with metacercaria of either F. hepatica or F. gigantica, they may acquire liver fluke)
1st Intermediate Host of Fasciola hepatica & Fasciola gigantica
snail
- Lymnea philippinensis
- Lymnea auricularia rubiginosa
2nd Intermediate Host of Fasciola hepatica & Fasciola gigantica
vegetations
- Ipomea obscura (kangkong)
- Nasturtium officinale (watercress)
habitat for Fasciola hepatica & Fasciola gigantica
liver parenchyma and gallbladder
infective stage for Fasciola hepatica & Fasciola gigantica
metacercaria
pathology for Fasciola hepatica & Fasciola gigantica
- fascioliasis (sheep liver rot / liver rot)
- liver atrophy
- pharyngeal suffocation
it is the result of the temporary lodgement of the fluke in the pharynx. give the MOT.
pharyngeal suffocation
ingestion
give 2 terms of pharyngeal suffocation
halzoun and mararra
pharyngeal suffocation terms:
originated from Lebanon
halzoun
pharyngeal suffocation terms:
originated from Sudan
mararra
laboratory diagnosis for Fasciola hepatica & Fasciola gigantica
stool exam
liver biopsy
PCR
drug of choice for Fasciola hepatica & Fasciola gigantica
Bithionol
Triclabendazole
LIVER FASCIOLIDS (MORPHOLOGY OF ADULT)
with cephalic cone which has well developed shoulder
Fasciola hepatica
LIVER FASCIOLIDS (MORPHOLOGY OF ADULT)
larger than F. hepatica
Fasciola gigantica
LIVER FASCIOLIDS (MORPHOLOGY OF ADULT)
less developed shoulder
Fasciola gigantica
LIVER FASCIOLIDS (MORPHOLOGY OF ADULT)
shorter cephalic cone
Fasciola gigantica
MORPHOLOGY OF ADULT (FASCIOLA HEPATICA)
with cephalic cone which has well developed shoulder
MORPHOLOGY OF ADULT (FASCIOLA HEPATICA)
- larger than F. hepatica
- less developed shoulder
- shorter cephalic cone
MORPHOLOGY OF LARVA (LIVER FASCIOLOIDS)
ALL STAGES ARE PRESENT
Miracidium
Sporocyst
Redia
Cercaria
Metacercaria
MORPHOLOGY OF EGG (LIVER FASCIOLOIDS)
large, operculated, unembryonated, yellowish-brown egg (Hen’s egg shape)
are termed to be Heterophyids
Clonorchis sinensis & Opisthorchis felineus
most important liver fluke of man
Clonorchis sinensis
a potential carcinogen and may cause liver dysfunction
Clonorchis sinensis
first described by McConnell
Opisthorchis felineus
other specie of opistorchis
Opistorchis viverrini
Opistorchis viverrini is also known as
Southeast Asian Liver Fluke
CLONORCHIS SINENSIS other names
Oriental Liver Fluke
Chinese Liver Fluke
OPISTORCHIS FELINEUS other names
Cat Liver Fluke
Siberia Liver Fluke
final host of clonorchis sinensis
man and other fish-eating vertebrae
final host of opisthorchis felineus
cats (cat liver fluke)
1st intermediate host of clonorchis sinensis
SNAIL
Family of the ff.:
Parafossarulus
Bulinus
Semisulcospira
Alocinma
Thiara
Melanoide
1st intermediate host of opisthorchis fenineus
SNAIL
Family Bithynia
2nd intermediate host of clonorchis sinensis
FISHES
Family Cyprinidae
2nd intermediate host of opisthorchis felineus
FISHES
Family of the ff.:
Cyprinidae
Cobitidae
HABITAT FOR BOTH CLINOCHIS SINENSIS AND OPISTHORCHIS FELINEUS
- LIVER PARENCHYMA
- ALSO IN PANCREATIC DUCT AND GALLBLADDER
INFECTIVE STAGE FOR CLONORCHIS SINENSIS AND OPISTHORCHIS FELINEUS
METACERCARIA
PATHOLOGY FOR CLONORCHIS SINENSIS AND OPISTHORCHIS FELINEUS
- periductal fibrosis
- gallbladder and liver carcinoma causing:
~ hepatocellular carcinoma
~ cholangiocarcinoma
~ most likely caused by C. sinensis - liver dysfunction
~ caused by C. sinensis
~ occurs on person severely infected over a long period of time - bile duct obstruction
LABORTORY DIAGNOSIS FOR CLINORCHIS SINENSIS AND OPISTHORCHIS FELINEUS
- stool exam
- serologic tests
- molecular tests
DRUG OF CHOICE FOR CLONORCHIS SINENSIS AND OPISTHORCHIS FELINEUS
PRAZIQUANTEL AND ALBENDAZOLE
MORPHOLOGY OF ADULT (CLONORCHIS SINENSIS AND OPISTHORCHIS FELINEUS)
- leaf-like with transparent tegument
- has vitellaria found in the middle third of the body
gravid uterus; uterus filled with ova
vitellaria
two large, highly branched testes arranged in tandem
Clonorchis sinensis (ADULT MORPHOLOGY)
lobate testes arranged obliquely
Opisthorchis felineus (ADULT MORPHOLOGY)
Opisthorchis felineus (SPECIFIC ADULT MORPHOLOGY)
lobate testes arranged obliquely
Clonorchis sinensis (SPECIFIC ADULT MORPHOLOGY)
two large, highly branched testes arranged in tandem
Morphology of Adult
for both:
- _________ with transparent tegument
- has _________ found in the middle third of the body
~ __________ - gravid uterus; uterus filled with ____
Clonorchis sinensis (SPECIFIC)
- two large, highly branched testes arranged in _________
Opisthorchis felineus (SPECIFIC)
- _________________ arranged obliquely
Morphology of Adult
for both:
- leaf-like with transparent tegument
- has vitellaria found in the middle third of the body
~ vitellaria - gravid uterus; uterus filled with ova
Clonorchis sinensis (SPECIFIC)
- two large, highly branched testes arranged in tandem
Opisthorchis felineus (SPECIFIC)
- lobate testes arranged obliquely
Morphology of Egg/Ova (for C. SINESIS AND O. FELINEUS):
- ________________, ovoid (pitcher-shaped / old-fashioned electric light bulb-shaped)
- distinct ___________________ that fits to the thickened rim of the eggshell
- thick rim located around the operculum (shoulders)
- small protuberance at the ____________________
~ in the opposite pole of the operculum
~ usually a ________-shaped
Morphology of Egg/Ova (for C. SINESIS AND O. FELINEUS):
- yellowish-brown, ovoid (pitcher-shaped / old-fashioned electric light bulb-shaped)
- distinct convex operculum that fits to the thickened rim of the eggshell
- thick rim located around the operculum (shoulders)
- small protuberance at the abopercular end
~ in the opposite pole of the operculum
~ usually a comma-shaped
SHAPE OF THE EGG/OVA OF C. SINENSIS AND O. FELINEUS
pitcher-shaped / old-fashioned electric light bulb-shaped
TRUE OR FALSE:
The egg/ova of fasciolids and heterophyids are distinguishable
FALSE
The egg/ova of fasciolids and heterophyids are reported as
fasciolid ova or heterophyid ova
responsible for human infection in West Africa
Dicrocoelium hospes
Dicrocoelium dendriticum AKA
Lanceolate / Lancet Fluke
final host of Dicrocoelium dendriticum
cattle / sheep
**also man serves as a final host
intermediate host of Dicrocoelium dendriticum
SNAIL
- Cochlicopa
- Helix
- Xerolenta
- Zebrina
2ND INTERMEDIATE HOST OF Dicrocoelium dendriticum
ants (Formica fusca)
- black ants
HABITAT OF Dicrocoelium dendriticum
biliary passage of the liver
infective stage of Dicrocoelium dendriticum
metacercaria
MOT of Dicrocoelium dendriticum
ingestion of 2nd intermediate host with metacercaria
pathology of Dicrocoelium dendriticum
cirrhosis / fibrosis of the liver
laboratory diagnosis of Dicrocoelium dendriticum
liver biopsy and PCR
morphology of adult Dicrocoelium dendriticum
- _______ and ________ at both sides
- _______-shaped
- flattened and tapered at both sides
- lancet-shaped
morphology of egg/ova Dicrocoelium dendriticum
- thick-shelled, operculated, and _________________
thick-shelled, operculated, and deep golden brown
INTESTINAL FLUKES
Fasciolopsis buski
Echinostoma ilocanum
Heterophyes heterophyes
Metagonimus yokogawai
3rd specie under the fasciolids
Fasciolopsis buski
largest fluke parasitizing man
Fasciolopsis buski
larger than F. gigantica
Fasciolopsis buski
Fasciolopsis buski aka
Giant Intestinal Fluke
final host of Fasciolopsis buski
man
1st intermediate host of Fasciolopsis buski
SNAIL
- segmentina
- hippeutis
2nd intermediate host of Fasciolopsis buski
VEGETATION
- Water caltrop (Trapa bicornis)
- Water chestnut (Eliocharis tuberosa)
- Kangkong / Morning Glory (Ipomea obscura)
- Lotus (Nymphoea lotus)
- Bamboo shoots (Zizania latifolia)
HABITAT of Fasciolopsis buski
small intestine