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MJ- Pharm Exam 3 > treatments- LL > Flashcards

treatments- LL Flashcards

1
Q

Essential tremor treatments?

A

“Players play the girl behind closed doors”

Propranolol: B2, brady, lightheaded, impotant
Primidone: sedation
Topiramate: Na channel, Concentration difficult
Gabapentin: Ca channel not a GABA rx, gait problmes
Botulism: head/voice tremor
Clonazepam: dependancy

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2
Q

Huntington disease treatment? “ben hunts for Oro”

A

Benazine: Deplete monoamine (dopa) = depression
Haloperidol: reduce dopamine = schizo, chorea, and tourettes
Fluphenazine: ???
Olanzapine: 5HT receptor= Schizo, tourettes (aripiprazole), QT Prolong

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3
Q

Tourettes tx? “ Erin Howlers profanity, but rarely acts”

A 
Education
Pimozide: failed occular accomidation
Haloperidol: D2 decrease, extra-pyramidal = parkinson like
Botulism: focal motor, or voic
Risparidone/Aripaprazole (tourette like)
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4
Q

RLS tx? “Lovers blend role playing games outside”

A

Intermit: Levo and benzos
Persist: (dope agonist) pramipexole, Ropinorole, gabapentin
Refractory: opioids

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5
Q

Wilsons disease Tx? “D-pen’s ring is trimed with iron and copper but not zinc”

A

D-penicillinamine: sulfa ring, give extra pyridozine
Trientine: Pulls Fe and Cu, low Fe = renal dx, high Fe= liver dx
Oral zinc = GI upset

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6
Q

ALS tx? “ Pertissis killed Ryan’s gluts, Butts take dedication.

A 
Rilozule: inhibits glut, pertusis rxn
Edaravone: free radical antioxidant
Badofen: gaba agonist: sedation
Tizanidine: DAD = drowsi, asthenia (weak), dizzy
Diazepam
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7
Q

MG TX? “ MY GOD! SLUDGEy diahhrea sticks on mine”

A

Pyridostigmine, Neostigmine: anticholinesterases = SLUDGE: salivation, lacrimation, urine, diah, GI, emisis

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8
Q

CNS effects

A

Idiosyncratic.

Idk what this means but brubs harped about his for a while.

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9
Q

In general are mono or multi anti seizure meds preferred?

A

mono

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10
Q

GABA and barbiturates have the same of different binding sites?

A

Different, but do basically the same thing. Gabas are drug B = No coma or death. Barbs are drug A = coma or death.

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11
Q

Generalized abscence Tx? “Even Val Lost Consciousness Tonight”

A

Ethosuximide: only Generalized, block Ca T channel, Ade= blood issues
Valproate: GABA, Box = Hepato, terato, pancreato
Lamotrigene: Na chan block, BOX = skin and diplopia
Clonazepam: Only infantil, sedation
Topiramate: Na chan block, confusion, conc. diff

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12
Q

Tonic-clonic meds? “ Lame Tory Leven has Behavioral issue”

A

Lamotrigene, Topiramate,

Levetriacetem - SV2A Decrease GLUT, behavioral issues

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13
Q

Focal siezure tx? “Chris Pine Lost Videos of The Genovian Princess “

A

Carbamazepine: Na channel, BOX= serious skin rash, HLA allele in asians, alopecia, Trigeminal neuraglia
Lamotrigene = Na, Box: skin and apolecia
Phenytoin = Na, decrease GLUT, BOX: CVD w/ rapid infusion, Nystagmus, Hirsutism, Gingival hyperplasia
Phenobarbital: enhance Gaba, sedation, behavioral
Topiramate: Na channel, conc. difficult
Valproate: BOX: hepato, terato, pancreato. mimics GABA
Gabapentin: decrease GLUT, Ataxia, weight gain

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14
Q

refractory focal meds? “Perry took viagra for Pauline

A

Pregabalin: same as gabapentin
Tiagabin: decrease conc. increase appetite
Peramparel: Rampage! = BOX: pschy and behavior issues
Vigabatrin: Box: perminant eye lose = poked in the eye

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15
Q

Myotonic Meds? “Val tried zipplinging and levetating”

A

Valporate
Zonisamide: Ca and Na channel, Sulfa rxn, kidney stones
Topiramate: Na, conc. difficulty,
Levetriacetam: SV2A, decrease GLUT, behavrioal

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16
Q

Canniboids

A

Think Lennox Gausaut and dravet light up

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17
Q

Stiripentol

A

Dravet loves to strip

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18
Q

What is status epilepticus?

A

siezure >30 mins and no baseline mental status regained

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19
Q

Why care about status?

A

Kill you, sustained depolarization = neuronal death

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20
Q

Status tx with 30 mins? (BENZOs)

A 
Loraz = Preffered for CNS
Midaz = IM/ IN/ Buccal, preffered
Diaz = Rectal
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21
Q

Status tx 30-60 mins?

Hydrate! Phebes very loose and limber

A

1st line = Hydantoins (Posphytoins)
2nd line = Phenobartibal, valproate
3rd line = Lacosamide, levetiracetam

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22
Q

Status tx >120 mins?

“1st, Mix penta patrons, then keep hydrating and inhale keto foods vivacously!”

A

1st - midazelam, pentobartibal, propofel

Then - Ketamine, hypothermia, anesthetic inhaled, keto diet and vagal stim

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23
Q 
What do you monitor with (status epi)
Diazepam
fosphenotoin (hillary)
Lorazepam
Pentobarbital (>120)
A 
Diazepam = vitals, EKG
fosphenotoin = vitals, EKG
Lorazepam = propylene dose
Pentobarbital  = vitals, EKG
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24
Q

How can you give midazolam? (status epi, >120)

A

buccal, IV, IN, IM

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25
Q

What turns on REM sleep?

What turns off REM sleep?

A 
on = cholinergic (parasymp)
Off = norepi
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26
Q

Do teens have a hard time falling asleep and old people have a hard time staying asleep?

A

Yeah

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27
Q

What can cause short term insomnia? (Dirty jobs and college sucks)

A

Death, jobs, exams, separation

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28
Q

Sedation vs hypnotics?

A 
Sedation = anxiolytic, relax you
Hypnotics = sets the mood... to sleep
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29
Q

What are the fat soluable vitamins?

A

ADEK

30
Q

What benzo is MC used for insomnia?

A 
eszopiclone = lunesta, but flurazepam is a true hypnotic. (Her flow is hypnotic)
Triazolam = homicide ideation (tried PA school)
31
Q

Where are benzo recepters found? Lck th Cl**

A

Limbic, thalamus, cerebral cortex

32
Q

What benzos have no metabolites? Lord OZark

A

Lorazepam, oxazepam, zolpidem

33
Q

what is antegrade amnesia? think Ruffi-colata

A

Cant remember anything after the hit.

34
Q

This is on the test

What is the antidote for all benzos? “Nil”

A

Flumazenil

35
Q

Are Zolpidem, Zalephon, and eszopiclone Benzos?

A

No

36
Q

What is a barbiTAL? tall glass

A

Like Liquor, drug class A (coma and death) that binds to GABA at a site DIFFERENT than Benzos

37
Q

Barbiturates ADE? Think alcohol

A

porphyria = so much chemical (blood-alcohol) that your increase anticoagulation

38
Q

Doxepin is used for what? think Duped

A

Duped the body into staying awake = sleep maintannatce insomnia

39
Q

What are the 2 sleeping antidepressants?

A

Mitrazapine, trazodone (priapism)

40
Q

What does suvorexant do?

OFF SIGNAL -

A

Turns off wake signal from Orexin (hypocretins)

cataplexy, narcolepsy like sxs

41
Q

Melatonin, think Circadian rhythmic sleep

A

melanie’s got circular rhythm

42
Q

Valerian

A

herbal root that smells like gym socks

43
Q

What are the 4 types of Narcolepsy.

What do Narcos do to pass the time? Play CHES

A

Cataplexy, Hallucinate, Excess daytime sleepiness, Sleep paralysis

44
Q

What are the EDS Meds? Excessive daytime sleepiness = Much more asleep

A

Modafinil, Armodafinil, methylphenidate (only for EDS not cataplexy)

45
Q

Modafinil and aRmodafinil are the R or L dimer

A

R dimer

46
Q

Cataplexy meds? (Freak out when you cant move) TSSM

A

Tricyclic, SSRI, SNRI, MAOI

47
Q

What causes hypersomnolance and cataplexy

A

Seregiline = decrease REM sleep and latency

48
Q

What does Na oxybate do?

A

Makes you sleep Shitty, changes sleep architeture, never add to another sleep med

49
Q

When do you give prophylatic IE drugs?

A

Gingival and gum bleeding procedures

50
Q

What is the MC entorococcus isolate?

A

E. faecalis, fecal = entero

51
Q

What does the sulbactam do in augmentin?

A

protects the beta ring

52
Q 
What do you monitor for
Daptomycin
Gentamicin
Linezolid
Rifampin
vanco
A

Daptomycin - rhabdo = CPK
Gentamicin - OTOtoxic, Nephro, NM block -
Linezolid - Thrombo, optic, peri neurophy - plateles
Rifampin - hepato - LFTs
Vanco -Redman, nephro conc. 15

53
Q

Prophylactic IE treat oral is? and when do you do it?

A

Amoxi

PV, Hx IE, unrepair congenital heart defect, transplant

54
Q

Anticholinergic ADE for many disease is…

A

Metallic taste and the dry as a hat bs

55
Q

What is the triple spray for COPD?

A

LABA + LAMA + ICS

56
Q

What does Roflumilast do in COPD?

A

Stop Pulmonary Remodeling!!

PDE4

57
Q

What are the 5 As of quitting smoking?

A

Ask, Advise, Assess, Assist, Arrange

58
Q

What are normal Sa02 and Pa02 values

A

Sa02 >88% or Pa02 >55

59
Q

Meds that trigger ASTHMA?

A

BANANAS

Benzalkonium ca
Acetaminophen, 
Non- selective b blocker
Asa
NSAID
Astham
Sulfites
60
Q

Astham triad?

A

NTI, narrow, tightness, inflammation

61
Q

Beta 2 agonists are (ATM)?

A

Albuterol, terbutaline, metaproternol

62
Q

What reverses CVD from theophylline?

A

Beta blockers

63
Q

1st line therapy for moderate to severe Astham is?

A

Corticosteroids (Bel, bud, dex, flunis, fluti, mome)

64
Q

Astham corticosteroids ADEs?

A

Fungal candica, adrenal suppresion, mild growth retardation in kids (not perminant)

65
Q

Why is Zileuton good for athletes?

A

No excessive, ASA allergy induced asthma

66
Q

Do you avoid cough suppressants and antibiotics for Acute bronchitis?

A

Yes - its a virus

67
Q

kids get acute bronchitis from what virus?

A

paraflu

68
Q

Bacterial Acute bronchitis is mostly due to?

A

Mycoplasma pneumonia

69
Q

RSV in acute bronchiolitis is treated by

A

Palivizumab (kids = ribavirin)

70
Q

Hallmark of Chronic bronchitis?

A

Cough, sputum, bacteria - Psuedomonas give aztrenam for 28 then torbimycin for 28

71
Q

CAP meds
healthy
comorbid viral and bacterial
Elderly

A

healthy = macro or tetracyline
comorbid viral and bacterial =osel/tamivir, MB or F
Elderly = Piper taco, or carb, cephalosporin or MB or F

72
Q

CAP meds

Non-ICU (comorbid)

A

Non-ICU - MB or F

MJ- Pharm Exam 3 (17 decks)

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