Treatment of Disorder(s) - MDD

Question 1

March et al (2007)

Answer 1

NIMH ‘treatment of adolescents with depression’ study - all treatments outperform placebo, antidepressants effective.

Question 2

Kirsch (2014)

Answer 2

effectiveness of antidepressants mostly placebo, “enhanced placebo effect”

Question 3

Hollon et al (2002)

Answer 3

suggests existing research excludes patients with severe depression. as HAM-D score increases (sig at 28), so did difference between drug & placebo

Question 4

Elkin et al (1989)

Answer 4

treatment groups didn’t differ in effectiveness for mild & moderate depression, drugs better for severe (& faster).

Question 5

DeRubeis et al (2005)

Answer 5

medication, CBT, placebo groups - CBT as effective as medication, depends on therapist’s skill & experience

Question 6

Goldapple et al (2004)

Answer 6

PET scan, depressed with CBT vs drugs before & after. different areas of brain affected for same physiological effects.

Question 7

Hodges & Oei (2007)

Answer 7

conceptual compatibility between CBT & chinese culture - similar values/processes so work well together.

Question 8

Kinzie et al (1987)

Answer 8

compliance when taking antidepressants, Asian ppts, 61% no TCA levels detected, 15% therapeutic TCA levels detected.

Question 9

Griner & Smith (2006)

Answer 9

meta-analysis - culturally adapted treatments. strong benefit of culturally adapted interventions, especially when targeted for specific groups of individuals based on background.

Question 10

Eyesenk (1952)

Answer 10

meta-analysis, 67% patients spontaneously recovered

Question 11

Smith & Glass (1977)

Answer 11

meta-analysis, therapy client better off than 75% untreated (would be 50% if it didn’t work)

Question 12

Wampold (2007)

Answer 12

compared psychotherapy with medicine - as effective.