TREATMENT MODALITIES FOR MENTALLY ILL PATIENTS Flashcards
Is usually the foundation for a successful treatment approach that can be use in combination with other approaches such as psychotherapy,etc..
PSYCHOPHARMACOLOGY
Most treatment for mental health disorderss are categorized into:
PSYCHOPHARMACOLOGY
SOMATIC
PSYCHOTHERAPY
Includes psychotherapy, behavior therapy techniques and hynotherapy.
PSYCHOTHERAPEUTIC TREATMENTS
Includes drugs, ECT, and other therapies that stimulates the transceanial magnetic stimulation and vagus nerve.
SOMATIC TREATMENT
Is the study of drug effects in clients and the expert use of drugs in the treatment of psychiatric conditions.
CLINICAL PSYCHOPHARMACOLOGY
Is a small organic molecule or peptide that participates in neural activity
NEUROCHEMICALS
Are chemical molecules that carry messages or signals from one nerve call to the next.
NEUROTRANSMITTER
Neurotransmitters can either be?
EXCITATORY OR INHIBITORY
Classifications of psychoactive or psychotherapeutic drugs?
ANTIPSYCHOTIC AGENTS/NEUROLEPTICS
ANTIMANIC
ANTIANXIETY & HYPNOTICS
ANTICONVULSANTS
ANTIDEPRESSANTS
ANTIPARKINSONISM OR ANTICHOLINERGIC
STIMULANTS
Is a procedure in which precise x-ray beams takes cross sectional images layer by layer?
COMPUTED TOMOGRAPHY
A type of body scan an energy field is created woth huge magnet and radio waves. The energy field is converted to a visual image or scan. Produces more tissue details and contrast than CT Scan.
MRI
Neurotransmitter that may result in neurotoxicity if levels are too high
GLUTAMATE
Controls sleep and wakefulness cycle, signal muscles to become alert
ACETYLCHOLINE
Enhance, prolong, or inhibit or limit the effects of principal neurotransmitters
NEUROPEPTIDES
Controls alertness, gastric secretions, cardiac stimulation, peripheral allerguc reactions?
HISTAMINE
Controls food intake and wakefulness, temperature regulation, pain control, sexual behaviors, regulation of emotion
SEROTONIN
Controls fight or flight response.
EPINEPHRINE
Causes chabges in attention, learning, and memory, sleep and wakefulness, mood
NOREPINEPHRINE
Controls comples movements, cognition, regulates emotional response.
DOPAMINE
Treats psychosis
ANTI PSYCHOTICS
Treat depression
ANTIDEPRESSANTS
Stabilize mood
MOOD STABILIZERS
Anti anxiety?
ANXIOLYTICS
A drug thay speeds up messages travelling between the brain and body?
STIMULANTS
Refers to a maximal therapeutic effect that a drug can achieve.
EFFICACY
Describez the amount of drug needed to achieve the maximum effect.
POTENCY
Is the time it takes for half of the drug to be removed from ythe bloodstream
HALF LIFE
Tricyclic antidepressants can take how many weeks before the patient can experience optimal therapeutic benefit?
4-6 WEEKS
Older adults require low or high dosage of meds that younger patients to experience therapeutic effect?
LOWER DOSAGE
What do you call it when medication are decreased gradually rather than abruptly?
TAPERING
Why do we do tapering of the medication or dosage?
BECAUSE OF POTENTIAL PROBLEMS WITH REBOUND( TEMPORARY RETURN OF SYMPTOMS) RECURRENCE(OF THE ORIGINAL SX) WITHDRAWAL (NEW SX RESULTING FROM DISCONT OF THE DRUG
Formerly known as neuroleptics
ANTIPSYCHOTIC DRUGS
Mechanism of action of antilsychotic meds?
Block receptors for the neurotransmitter dopamine
Antipsychotic drugs classification
CONVETIONAL OR FIRST GENERATION ANTIPSYCHOTIC
ATYPICAL OR SECOND GENERATION ANTIPSYCHOTICS
THIRD GENERATION ANTIPSYCHOTICS
Are potent antagonist blockers and are effective in treating target symptoms but produces many EPS effects
CONVENTIONAL/ FIRST GEN ANTIPSYCHOTICS
Examples of first gen antipsychotics?
HALOPERIDOL(HALDOL)
CHLORPROMAZINE(THORAZINE)
Examples of 2nd gen or atypical antilpsychotic?
CLOZAPINE
RISPERIDONE
OLANZAPINE
QUETIAPINE
Are effective in treating the depressive aspects of schizo?
SSRIs (under atypical or 2nd gen)
They enhance or preserve dopaminergic transmission when it is too low and reduce it when it is too high
DOPAMINE SYSTEM STABILIZERS( THIRD GEN ANTI PSYCHOTIC)
Examples of third gen drug anti psychotic
ARIPIPRAZOLE
BREXPIPRAZOLE
Common side effects of 3rd gen anti psych?
SEDATION
WEIGHT GAIN
AKATHISIA
HEADACHE
ANXIETY
NAUSEA
A time release form of intramuscular medication for maintenance therapy
DEPOT INJECTION
After latients condition is stabilized with oral doses of these medication, administration by depot injection is required every 2-4 weeks to maintain therapeutic effects
DECANOATE FLUPHENAZINE(7-28 DAYS) OILY FORM-IM
DECANOATE HALOPERIDOL( DURATION OF 4 WKS)
Other band in depot form:
Risperidone 25 mg given every?
Olanzapine pamoate 210 mg every?
Or 405 mg every?
2 WKS
2 WKS
4 WKS
Includes acute muscualr rigidity and cramping, a stiff or thick tongue with difficulty swallowing. In severe cases, laryngospasm and respiratory difficulties
ACUTE DYSTONIA
Likely to occur in the 1st wk of tx. In patients younger than 40 yrs, in males and those receiving high potency drugs such as haloperidol
ACUTE DYSTONIA
Other sx of acute dystonia:
TORTICOLLIS
OPISTHOTONOUS
OCULOGYRIC CRISIS
ACUTE DYSTONIC REACTION
Twisted head and neck due to spasm or stiffness in the muscle group
TORTICOLLIS
Eyes rolled back in a locked position
OCULOGYRIC CRISIS
Tightness in the entire body with the head, back, and arched neck
OPISTHOTONOUS
Can be painful and frightening to the patient
ACUTE DYSTONIC REACTION
Treatment for Acute Dystonia
ANTICHOLINERGIC DRUGS( BENZTROPINE MESYLATE-COGENTIN IM/ORAL)
DIPHENHYDRAMINE(BENADRYL IM/IV)
Sx resembles those of parkinson disease. Stiff stooped posture, mask like facies, decreased arm swing, shuffling, festinating gait, cogwheel rigidity, drooling, tremor, bradycardia and coarse pill rolling of the thumb and fingers while at rest.
PSEUDOPARKINSONISM
How is parkinsonism treated?
By changing to an antipsychotic medication that has lower incidence of EPS or by adding an oral anticholinergic agent
An intense need to move about, patient appears restless, or anxious or agitated, often with rigid posture or gait or lack of spontaneous gestures
AKATHISIA
Treatment for akathisia?
Change the antipsychotic med or by addition of an oral agent such as beta blocker, anticholinergic, benzodiazepine
Is a potentially fatal idiosyncratic reaction to an anti psychotic drug
NEUROLEPTIC MALIGNANT SYNDROME
A syndrome of inappropriate involuntary movements, is most commonly caused by long term use of conventional antipsychotic drug. Sx include involuntary movements of the tongue, facial and neck muscles, upper and lower extremities and truncal musculature
TARDIVE DYSKINESIA
Characteristic of tardive dyskinesia
Tongue thrusting and protruding
Lip smacking
Blinking and grimacing
1st drugs to treat tardive dyskinesia
VALBENAZINE
DEUTETRABENAZINE
Anticholinergic side effects
ORTHOSTATIC HYPOTENSION
DRY MOUTH
CONSTIPATION
URINARY HESITANCE OR RETENTION
BLURRED NEAR VISION
DRY EYES
PHOTOPHOBIA
NASAL CONGESTION
DECREASED MEMORY
Prodices fewer traditional side effects than do most antipsychotic drugs but it has fatal side effect of agranulocytosis
CLOZAPINE
Severe low level of white blood cells called neutrophils
AGRANULOCYTOSIS
Why do patient should take or drink sugar free hard candy?
To ease dry mouth
Stool softeners are allowed for patients but not laxatives. Why?
They interfere with the absorption of medication
What if the latient forgot a dose of antipsychotic medication? He or she can take the missed dose if it is only?
3 OR 4 HOURS LATE . IF MORE THAN 4 HRS OVERDUE, PT CAN OMIT THE DOSE
Are primary used in the tx of major depressive illness, anxiety disorders, depressed phase of bipolar disorder and psychotic depression?
ANTIDEPRESSANTS DRUG
Antidepressant drug interacts with?
NORE AND SERO
What are the four groups of antidepressants?
●TRICYCLIC AND THE RELATED CYCLIC ANTIDEPRESSANTS
●SSRIs
●MAOIs
●OTHER ANTIDEP SUCH AS DESVENLAFAXINE, VANLAFAXINE, DULOXETINE,NEFAZODONE
Cause varying degrees of sedation, orthostatic hypotension, and anticholinergic side effects
CYCLIC ANTIDEP
Were discovered to have a positive effect on depression. May have a low incidence of sedation and anticholinergic effects but must use with extreme caution for several reasons.
MAOIs
Life threatening side effects of taking MAOIs
HYPERTENSIVE CRISIS
Potentially lethal in overdose and pose a potential risk in clients with depression who maybe considering suicide
MAOIs
Preferred drugs for clients at high risk for suicide
SSRIs
Are often better choices for those who are potentially suicidal because they carry no risk or lethal overdose, however SSRIs are effective only for mild and moderate depression.
SSRIs
VENLAFAXINE
NEFAZODONE
BUPROPION
Side effects of SSRIs
ANXIETY
AGITATION
AKATHISIA
NAUSEA
SEXUAL DYSFUNTION
INSOMNIA
DIEARRHEA
HEADACHE
Side effects of cyclic antidepressants
DRY MOUTH
CONSTIPATION
URINARY HESITANCY OR RETENTION
DRY NASAL PASSAGES
BLURRED NEAR VISION
ORTHO HYPO
SEDATION
WEIGHT GAIN
TACHYCARDIA
Side effects of MAOIs
DAYTIME SEDATION
INSOMNIA
WEIGHT GAIN
DRY MOUTH
ORTHO HYLO
SEXUAL DYSFUNCTION
An uncommon but potentially serious drug interaction which results from taking MAOIs and SSRIs at the same time
SEROTONIN SYNDROME
Sx of serotonin syndrome
AGITATION
SWEATING
FEVER
TACHYCARDIA
HYPOTENSION
RIGIDITY
HYPERREFLEXA
COMA
DEATH IN EXTREME REACTION
When to take SSRIs
1st thing in the morning unless sedation is a problem
If the dose of SSRIs was forgotten the client can take the next dose after how many hours of the missed?
8 HOURS
If the client taking cyclic forgot the dose , he/she can take the next dose within how many hrs of the missed dose?
3 HOURS OR OMIT THE DOSE FOR THAT DAY
Are used to treat bipolar disorder by stabilizing the client’s mood, preventing or minimizing the highs and lows that characterize bipolar illnesses and treating acute episodes of mania
MOOD STABILIZING DRUGS
Is the most established mood stabilizer
LITHIUM
Anticonvulsants used as mood stabilizers which are also effective
CARBAMEZEPINE(TEGRETOL)
VALPROIC ACID(DEPAKOTE)
Other anticonvulsants as mood stabilizers:
GABAPENTINE
TOPIRAMATE
OXCARBAZEPINE
LAMOTRIGINE
CLONAZEPAM
The normal serum lithium level on the blood
0.5 mEq/L to 1.5 mEq/L
Lithium levels should be monitored for how many days?
Every 2-3 days. Then should be monitored weekly. Once patient is stable it is check onvce a month.