Treatment for Anxiety Flashcards
What is the main treatment for anxiety?
SSRIs are first line in all anxiety disorders
When may benzodiazepines be used for anxiety?
Benzodiazepines may be used alongside anti-psychotics in situations where rapid tranquilisation is required as there is an acute harm to self or others.
If benzodiazepines are used for short term for the initation of symptomatic relief they do not have the dependence risk associated.
Which TCAs are used and in which specific anxiety conditions?
Clomipramine and Imipramine
Used first line for panic disorder when SSRI is unsuitable - also used in OCD
In practice why are TCAs less widely used for anxiety?
Rarely used due to side effects, toxicity in overdose and difficulty reaching the therapeutic level required.
How long do SSRIs take to work in anxiety disorder?
Response is up to 12 weeks which is remarkably longer than when SSRIs are used in the treatment of depression.
Why is extensive monitoring required at the beginning of SSRI therapy for anxiety?
Patients are likely to experience an initial worsening of symptoms which an increased risk of suicidal thinking and self-harm.
The risk should be monitored weekly and the dose slowly up-titrated in response to the patients tolerability usually every 2 weeks.
If SSRIs are to be discontinued how long should it be done over?
Normally over 4 weeks to prevent discontinuation symptoms occurring.
How should the discontinuation of Diazepam be managed?
Diazepam in particular has a long half life and therefore the discontinuation effects of the medication will not become apparent until four weeks after the medication has been stopped.
The last few mg of Diazepam is normally the hardest to stop due to psychological dependence - can use syrup and add 5mL of diluent to wean off, however this is unlicensed.
What are some of the SSRIs used as first-line treatment for anxiety?
Escitalopram
Fluoxetine
Paroxetine
Sertraline
Citalopram
How effective are medications used in anxiety?
No medicine provides a cure for anxiety however they can help with symptomatic relief.
For example in PTSD symptoms are controlled by treatment and they can help recovery however they do not erase the memories.
OCD symptoms can be reduced by adequate treatment and can help psychological therapies be effective which in severe OCD wouldn’t allow.
What are some non-pharmacological interventions for anxiety?
Counselling
CBT
Anxiety management - group or individual
Self help - avoiding caffeine
Relaxation techniques
Self-help groups/books
Lifestyle changes
What is Step 1 of the stepped care approach for anxiety?
Recognise, asses and diagnose the patient with generalised anxiety
Educate them on the condition, treatment options or monitor
What is Step 2 of the stepped care approach for anxiety?
Diagnosed GAD that has not improved after education and active monitoring in primary care
Low intensity psychological interventions
Self-help psychoeducation groups for mild anxiety
What is Step 3 of the stepped care approach for anxiety?
GAD with an inadequate response to Step 2 interventions or marked functional impairment
High intensity psychological interventions are required (CBT/applied relaxation) or drug treatment
What is Step 4 of the stepped care approach for anxiety?
Complex treatment - refractory GAD, marked functional impairment with a high risk of neglect
Specialist treatment, inpatient stay, crisis service, day hospital
Complex drug and/or psychological treatment interventions