Treatment

Question 1

What is a randomised control trial?

Answer 1

Sufficient sample size, random allocation can result in comparable distribution of known and unknown confounding factors

Question 2

What is the absolute risk reduction?

Answer 2

Experimental event rate- Control event rate

Question 3

What is the numbers needed to treat (NNT) equal to?

Answer 3

The reciprocal of the absolute risk reduction

Question 4

What are the different types of biases?

Answer 4

Allocation bias 
Performance bias
Attrition bias 
Detection bias 
Reporting bias

Question 5

How do you prevent allocation bias?

Answer 5

Randomisation and concealment

Question 6

What is meant by attrition bias?

Answer 6

Withdrawl from the trial

Question 7

What is meant by detection bias?

Answer 7

outcomes detected differently between the two arms of the trial

Question 8

What is meant by reporting bias?

Answer 8

Outcomes/harms reported differently by patients

Question 9

What is meant by internal validity?

Answer 9

The extent to which the experiment is free from errors and any difference in measurement is due to independent variable

Question 10

What is meant by external validity?

Answer 10

Extent to which the research results can be inferred to world at large
Measure of accuracy of the experiment