Treatment

Question 1

What is the pathway that we follow to treat sepsis?

Answer 1

Sepsis 6

Question 2

What components make up the sepsis 6?

Answer 2

1. Oxygen
2. IV fluids
3. IV antibiotics
4. Lactate
5. Urine output
6. Blood cultures

Question 3

How much oxygen should be given?

Answer 3

15 litres initially then titrated to target saturations (94-98%)

Question 4

What device should be used when delivering the oxygen?

Answer 4

Non re-breathe mask

Question 5

How much oxygen (%) does a non-rebreathe mask deliver?

Answer 5

60-98%

Question 6

When should blood cultures be taken?

Answer 6

Prior to antibiotic therapy

Question 7

What else can be taken to determine the source of infection?

Answer 7

1. Urine
2. Wound
3. Routine bloods

Question 8

When should antibiotics be given?

Answer 8

Preferably after blood cultures have been taken

Question 9

What antibiotics will be given?

Answer 9

Refer to trust policy until blood cultures come back

Question 10

Why should fluids be prescribed?

Answer 10

1. To reduce organ dysfunction
2. Increases organ perfusion
3. Possible improved cardiac output

Question 11

What type of fluids should be prescribed?

Answer 11

A crystalloid (usually hartmanns)

Question 12

How much fluid should be prescribed?

Answer 12

maximum 30ml/kg (divided into boluses of approx 10ml/kg)

Question 13

What is lactate?

Answer 13

Lactate is a stress response. It is located all over the body.

Question 14

What are routine bloods?

Answer 14

1. Full blood count (FBC)
2. Urea and electrolytes (U&E’s)
   3 Liver function test (LFT’s)
3. Clotting

Question 15

What can be done to monitor urine output?

Answer 15

1. catheter insertion

2. fluid balance chart