Treatment

Question 1

Goal

Answer 1

50% reduction on LDL levels

Question 2

Decision to treat

Answer 2

estimate risk using baseline levels

Question 3

Recommendations: age 20 years older, not on lipid medications

Answer 3

Measurement of either a fasting or nonfasting level is effective

Question 4

Recommendations: In adults 20 years + with nofasting trigylceride lves > 400

Answer 4

repeat lipid pabel in fasting state

Question 5

Recommendations: LLDL < 70

Answer 5

measurent of diretc LDL or modified LDL os resonable to improve accuracy

Question 6

Recommendations: 20yeas+ w/o personal hx ASCVD but fhx of premature ASCVD or genetic hyperlipidemia

Answer 6

measure fasting lipid profile

Question 7

Lifestyle modifications: Diet

Answer 7

fruit, vegetables, fiber, low fat dairy, poultry, fish, nontropical oils is ok; limit sweets, refined carbs, red and processed meats; avoid trans fats

Question 8

Lifestyle modications: Physical activity

Answer 8

stimulates activity if lipopreitn lopase; lower tricglerscies and VLDL, promote CV fitnees and weih loss; 150 minutes/week moder teinteisyt or 75 minues;wee of vigros areboci exerse (swimming, bikin, playing teniis)

Question 9

Re-assessment

Answer 9

Low risk patients starting with TLC: 2-3 visits in 3 months

Question 10

Recommendations for drug thx

Answer 10

(1) Select patient with moderately high LDL > 160 (2) Patients with very high LDL > 190. (3) High intensity statin plus ezetimibe and/or PCKS9 inhibitor for the pt at very high risk (hx multiple major ASCVD events)