travers 2 Flashcards
physical (direct) interaction
stimulus with membrane protein opens ion channel
somatosensory, vesticular, auditory, taste
molecular interaction
stimulus with membrane protein eg g-protein
vision, taste, olfaction
direct transduction in taste system
sodium enters thru epithelial sodium channels
action potential lead to calcium entry
release of atp as neurotransmitter
molecular g-protein coupled transduction for sweet stimuli
sugars bind to receptor couple to g-protein
release of intracellular ca activates trpm5 channel
depolarization leads to action potentials and release of neurotransmitter atp
trp channels
family of ion channels comprised of 6 transmembrane domains with channel btween 5th and 6th
cation ion channel that can pass calcium with a large variety of activating mechanism
presynaptic inhibition
hyperpolarized axon terminal leads to less calcium entry and less nt release
postsynaptic inhibition
epsp and ipsp interact- spatial and temporal summation